Nair Swetha M, Sahu Arpita, Prasad Apurva, George Asha Mary, Goel Atul, Gupta Tejpal
Department of Radiodiagnosis, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India.
Department of Neurosurgery, Bhatia General Hospital, Mumbai, Maharashtra, India.
Indian J Radiol Imaging. 2023 Dec 4;34(2):351-355. doi: 10.1055/s-0043-1777012. eCollection 2024 Apr.
Isocitrate dehydrogenase mutant gliomas generally have a better prognosis than their wild-type counterpart. Recurrences are generally within the radiation field in the primary tumoral bed. Remote recurrence is uncommon and is usually intraparenchymal. Transformation to a higher grade has been observed with TP53 mutants. Presentation of glioma as an extra-axial lesion is extremely uncommon. No such cases of remote intracranial extra-axial recurrence have been reported in the literature. We describe the unique imaging findings in this case and attempt to formulate possible diagnoses. Intraoperative and pathological findings confirmed this unusual recurrence pattern.
异柠檬酸脱氢酶突变型胶质瘤的预后通常比野生型胶质瘤更好。复发一般发生在原发肿瘤床的放疗区域内。远处复发并不常见,通常发生在脑实质内。TP53突变型胶质瘤已观察到向更高级别转变的情况。胶质瘤表现为轴外病变极为罕见。文献中尚未报道过这种远处颅内轴外复发的病例。我们描述了该病例独特的影像学表现,并尝试做出可能的诊断。术中及病理结果证实了这种不寻常的复发模式。