Suppr超能文献

探究具有重要药用价值的氨基酸 L-异亮氨酸和 L-络氨酸的溶解度:在不同混合溶剂体系中阐明溶剂化热力学。

Probing pharmaceutically important amino acids L-isoleucine and L-tyrosine Solubilities: Unraveling the solvation thermodynamics in diverse mixed solvent systems.

机构信息

Department of Chemistry, University of Kalyani, Kalyani 741235, Nadia, India; Department of Chemistry, JIS College of Engineering, Kalyani 741235, Nadia, India.

Department of Chemistry, University of Kalyani, Kalyani 741235, Nadia, India.

出版信息

Biophys Chem. 2024 Jun;309:107229. doi: 10.1016/j.bpc.2024.107229. Epub 2024 Mar 27.

Abstract

The study specifically investigates the solubilities of L-isoleucine and L-tyrosine in water-mixed solvent systems (DMF, DMSO, and ACN), exploring the behaviour of amino acids in complex environments. The experimental methods prioritize meticulous solvent purification to ensure reliable results. The work explores solubility data, uncovering temperature-dependent trends and intricate interactions influencing solubility in the chosen mixed solvent systems. The study emphasizes the impact of thermodynamic properties, solvent-solvent interactions, and amino acid structure on solubility patterns. The broader implications highlight the relevance of understanding amino acid behaviour in diverse solvent environments, offering potential applications in cosmetics and pharmaceutical industries. The distinct solubility patterns contribute valuable insights, enhancing on the understanding of the solution stability and interactions of L-isoleucine and L-tyrosine in different solvent systems. In conclusion, work suggests the enhanced utilization of L-isoleucine and L-tyrosine in various industries, driven by a profound understanding of their solubility in mixed solvent systems. The research expands our knowledge of amino acid behaviour, paving the way for advancements in industries relying on protein-based products and technologies.

摘要

该研究专门调查了 L-异亮氨酸和 L-酪氨酸在水混合溶剂体系(DMF、DMSO 和 ACN)中的溶解度,探索了氨基酸在复杂环境中的行为。实验方法优先考虑仔细的溶剂纯化,以确保可靠的结果。该工作探索了溶解度数据,揭示了温度依赖性趋势和复杂的相互作用对所选混合溶剂体系中溶解度的影响。该研究强调了热力学性质、溶剂-溶剂相互作用和氨基酸结构对溶解度模式的影响。更广泛的影响强调了理解氨基酸在不同溶剂环境中的行为的相关性,为化妆品和制药行业提供了潜在的应用。不同的溶解度模式提供了有价值的见解,增强了对 L-异亮氨酸和 L-酪氨酸在不同溶剂系统中稳定性和相互作用的理解。总之,该工作表明,通过深入了解其在混合溶剂系统中的溶解度,可以在各个行业中更有效地利用 L-异亮氨酸和 L-酪氨酸。该研究扩展了我们对氨基酸行为的认识,为依赖蛋白质产品和技术的行业的发展铺平了道路。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验