Centre for High-Pressure Research, School of Physics, Bharathidasan University, Tiruchirappalli, Tamil Nadu, 620024, India.
Centre for Applied Research, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Tamil Nadu, 602105, India.
Mikrochim Acta. 2024 Apr 1;191(4):226. doi: 10.1007/s00604-024-06267-7.
The focus of this paper is laid on synthesizing layered compounds of CuMoO and TiCTx using a simple wet chemical etching method and sonochemical method to enable rapid detection of rutin using an electrochemical sensor. Following structural examinations using XRD, surface morphology analysis using SEM, and chemical composition state analysis using XPS, the obtained CuMoO/TiCTx nanocomposite electrocatalyst was confirmed and characterized. By employing cyclic voltammetry and differential pulse voltammetry, the electrochemical properties of rutin on a CuMoO/TiCTx modified electrode were examined, including its stability and response to variations in pH, loading, sweep rate, and interference. The CuMoO/TiCTx modified electrode demonstrates rapid rutin sensing under optimal conditions and offers a linear range of 1 µΜ to 15 µΜ, thereby improving the minimal detection limit (LOD) to 42.9 nM. According to electrochemical analysis, the CuMoO/TiCTx electrode also demonstrated cyclic stability and long-lasting anti-interference capabilities. The CuMoO/TiCTx nanocomposite demonstrated acceptable recoveries when used to sense RT in apple and grape samples. In comparison to other interfering sample analytes encountered in the current study, the developed sensor demonstrated high selectivity and anti-interference performance. As a result, our research to design of high-performance electrochemical sensors in the biomedical and therapeutic fields.
本文的重点是使用简单的湿化学蚀刻法和超声化学法合成 CuMoO 和 TiCTx 的层状化合物，以电化学传感器快速检测芦丁。通过 XRD 进行结构检查、SEM 进行表面形貌分析和 XPS 进行化学组成状态分析，对得到的 CuMoO/TiCTx 纳米复合材料电催化剂进行了确认和表征。通过循环伏安法和差分脉冲伏安法，研究了 CuMoO/TiCTx 修饰电极上芦丁的电化学性质，包括其在 pH 值、负载量、扫描速率和干扰变化下的稳定性和响应。在最佳条件下，CuMoO/TiCTx 修饰电极对芦丁的检测速度较快，线性范围为 1µM 至 15µM，从而将最小检测限（LOD）提高到 42.9 nM。根据电化学分析，CuMoO/TiCTx 电极还表现出循环稳定性和持久的抗干扰能力。CuMoO/TiCTx 纳米复合材料在用于检测苹果和葡萄样品中的 RT 时表现出可接受的回收率。与当前研究中遇到的其他干扰样品分析物相比，开发的传感器表现出高选择性和抗干扰性能。因此，我们的研究旨在设计用于生物医学和治疗领域的高性能电化学传感器。
