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退伍军人事务医疗系统中种族/族裔少数群体在获取主动脉瓣狭窄新疗法方面的术前障碍。

Pre-procedural barriers to accessing novel treatments for aortic stenosis among racial/ethnic minorities in the veterans affairs healthcare system.

作者信息

Kerkar Ashwini, Gummidipundi Santosh, Heidenreich Paul A, Yong Celina M

机构信息

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford Cardiovascular Institute, Stanford, CA, USA.

Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA, USA.

出版信息

Am Heart J Plus. 2021 Jun 24;5:100029. doi: 10.1016/j.ahjo.2021.100029. eCollection 2021 May.

Abstract

BACKGROUND

Novel structural heart procedures offer life-saving treatment advantages, yet little is known about pre-procedural barriers to care by race/ethnicity.

METHODS

All echocardiograms performed at a Veterans Affairs hospital from 2015 to 2019 were reviewed to identify patients with severe aortic stenosis and their access to transcatheter aortic valve replacement (TAVR) by race/ethnicity.

RESULTS

From 19,403 echocardiograms, 355 individuals were identified to have severe aortic stenosis (72.6% White, 9.8% Hispanic, 3.9% Black). There was a non-significant trend towards increased TAVR treatment among White compared to non-White patients (OR 2.02, CI 0.96-4.24,  = 0.063), which attenuated after adjustment for age and comorbidities. Reasons for not undergoing replacement included poor procedural candidacy (25.3%), loss of follow-up (17.8%), and patient refusal (16.4%).

CONCLUSIONS

Racial/ethnic inequities were not detected in novel structural heart treatment within the VA. However, a high proportion of eligible patients did not receive procedural treatment due to patient refusal or loss of follow-up, highlighting barriers that require further study.

摘要

背景

新型结构性心脏手术具有挽救生命的治疗优势,但对于按种族/族裔划分的术前护理障碍知之甚少。

方法

回顾了2015年至2019年在一家退伍军人事务医院进行的所有超声心动图检查,以确定患有严重主动脉瓣狭窄的患者及其按种族/族裔接受经导管主动脉瓣置换术(TAVR)的情况。

结果

在19403份超声心动图检查中,355人被确定患有严重主动脉瓣狭窄(72.6%为白人,9.8%为西班牙裔,3.9%为黑人)。与非白人患者相比,白人患者接受TAVR治疗的趋势虽不显著但有所增加(比值比2.02,可信区间0.96 - 4.24,P = 0.063),在对年龄和合并症进行调整后这种趋势减弱。未进行置换的原因包括手术候选资格不佳(25.3%)、失访(17.8%)和患者拒绝(16.4%)。

结论

在退伍军人事务部的新型结构性心脏治疗中未发现种族/族裔不平等现象。然而,由于患者拒绝或失访,很大一部分符合条件的患者未接受手术治疗,这突出了需要进一步研究的障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15d6/10976283/7ef6919b242f/gr1.jpg

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