Johnson Ryan, Shaffer Annabelle, Tang Ashley, Tsai Kathryn, Guglielmi Gina, Arnold Paul M
1Department of Neurosurgery, Carle Foundation Hospital, Urbana, Illinois; and.
2Carle Illinois College of Medicine, University of Illinois Urbana-Champaign, Urbana, Illinois.
J Neurosurg Case Lessons. 2024 Apr 1;7(14). doi: 10.3171/CASE23646.
Spinal metastases are commonly seen in patients with cancer and often indicate a poor prognosis. Treatment can include curative or palliative surgery, chemotherapy, and radiation therapy. The surgical approach varies widely on the basis of the affected region of the spine, the location of the tumor (anterior versus posterior), the goal of surgery, the health of the patient, and surgeon preference.
The authors present a case of a 68-year-old male with intractable lower-back pain and substantially diminished ambulation. Diagnostic imaging revealed a lumbar metastasis from a cholangiocarcinoma primary at L2-3 (4.5 cm anteroposterior × 5.7 cm transverse × 7.0 cm craniocaudal). The patient underwent a 2-level vertebrectomy with expandable cage placement and T10 to S2 fusion via a posterior-only approach. The patient regained much of his mobility and quality of life after the surgery.
Although this was a high-risk surgery, the authors show that a posterior-only approach can be used for lumbar vertebrectomies and fusion when necessary. Palliative surgeries carrying a high risk, especially in the setting of a limited prognosis, should include multidisciplinary deliberations and a thorough discussion of the risks and outcome expectations with the patient.
脊柱转移瘤在癌症患者中很常见,通常预示着预后不良。治疗方法可包括根治性或姑息性手术、化疗和放疗。手术方式因脊柱受累区域、肿瘤位置(前部与后部)、手术目标、患者健康状况以及外科医生的偏好而有很大差异。
作者报告了一例68岁男性患者,患有顽固性下背部疼痛且行走能力大幅下降。诊断性影像学检查显示L2 - 3处有来自胆管癌原发灶的腰椎转移瘤(前后径4.5 cm×横径5.7 cm×头尾径7.0 cm)。该患者通过单纯后路入路接受了两级椎体切除术、可扩张椎间融合器置入以及T10至S2融合术。术后患者恢复了大部分活动能力和生活质量。
尽管这是一台高风险手术,但作者表明,必要时单纯后路入路可用于腰椎椎体切除术和融合术。高风险的姑息性手术,尤其是在预后有限的情况下,应包括多学科会诊,并与患者彻底讨论风险和预期结果。