Department of Human Neurosciences, Sapienza University of Rome, Italy.
Department of Human Neurosciences, Sapienza University of Rome, Italy.
J Clin Neurosci. 2024 May;123:100-117. doi: 10.1016/j.jocn.2024.03.032. Epub 2024 Apr 1.
Parkinson's disease (PD) affects Quality of Life (QoL), since it is responsible for cognitive impairment, non-motor, and motor symptoms. Outcome measures are fundamental for evaluating treatment's effect on QoL over time. This systematic review aimed to identify the psychometric properties of PDQ-39 and PDQ-8 in the different populations in which they were validated. The electronic databases systematically searched are MEDLINE (via PubMed), CINAHL, SCOPUS, and Web of Science; the research was conducted in July 2023. The psychometric properties considered were those of the COnsensus-based Standards for the selection of health Measurement Instruments (COSMIN) checklist. Risk of bias was assessed using the COSMIN checklist. The search identified 1306 articles. 398 duplicates were eliminated; 908 articles were analyzed reading title and abstract; 799 were finally excluded because used PDQ-39 and PDQ-8 as outcome measures or were not dealing with psychometric properties; 66 articles were excluded after reading the full text. 43 articles were included in the review; meta-analysis showed all the Cronbach's alpha values were statistically significant for all the subscales of PDQ-39 and PDQ-8. PDQ-39 demonstrated to be a specific HRQoL questionnaire that is correlated with generic HRQoL questionnaires, in fact in many studies included in the review, correlations with SF-36 were found. In the last studies about psychometric properties of PDQ-8 emerged that it is a practical and informative instrument that can be easily used in clinical settings, especially in busy ones, but also in large-scale studies in which a brief instrument would be preferred.
帕金森病（PD）影响生活质量（QoL），因为它会导致认知障碍、非运动和运动症状。结果测量对于评估治疗对 QoL 的长期影响至关重要。本系统评价旨在确定 PDQ-39 和 PDQ-8 在验证时的不同人群中的心理测量特性。系统检索的电子数据库包括 MEDLINE（通过 PubMed）、CINAHL、SCOPUS 和 Web of Science；研究于 2023 年 7 月进行。考虑的心理测量特性是基于共识的健康测量仪器选择标准（COSMIN）清单。使用 COSMIN 清单评估偏倚风险。搜索确定了 1306 篇文章。398 篇重复文章被排除；908 篇文章通过阅读标题和摘要进行了分析；799 篇文章最终被排除，因为它们使用 PDQ-39 和 PDQ-8 作为结果测量或不涉及心理测量特性；阅读全文后排除了 66 篇文章。共有 43 篇文章纳入综述；荟萃分析显示，PDQ-39 和 PDQ-8 的所有分量表的克朗巴赫's alpha 值均具有统计学意义。PDQ-39 被证明是一种特定的 HRQoL 问卷，与通用 HRQoL 问卷相关，实际上，在综述中纳入的许多研究中，与 SF-36 存在相关性。在最近关于 PDQ-8 的心理测量特性的研究中发现，它是一种实用且信息量丰富的工具，可在临床环境中轻松使用，特别是在繁忙的环境中，也可在大型研究中使用，因为在这些研究中，人们更倾向于使用简短的工具。
