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烧伤瘢痕内同时发生癌与肉瘤:治疗难题。

Synchronous carcinoma and sarcoma in a burn scar: a treatment conundrum.

机构信息

General Surgery, BGS Global Institute of Medical Sciences, Bangalore, KARNATAKA, India.

Department of Surgery, SDM College of Medical Sciences and Hospital, Dharwad, Karnataka, India

出版信息

BMJ Case Rep. 2024 Apr 1;17(4):e257102. doi: 10.1136/bcr-2023-257102.

Abstract

Marjolijn's ulcer is a malignant ulcer in a burn scar. Types of malignancy are squamous cell carcinoma, basal cell carcinoma and malignant melanoma. Soft tissue sarcoma case reports indicate only one type of cancer. We present a patient in her 60s with a 10-year-old burn scar developing a biopsy-proven squamous cell carcinoma on the lateral aspect of the left thigh with metastatic superficial inguinal node. A wide excision and grafting of ulcer with ilioinguinal dissection done on left side. On the 12th postoperative day 2, subcutaneous swellings adjacent to the grafted area developed, on biopsy revealed to be pleomorphic sarcoma. PET CT scan revealed tumour deposits in the muscles of the left lower limb, liver and lung. There are no case reports of synchronous carcinoma and sarcoma in a burn scar. The case is reported for its rarity and the decision-making dilemma.

摘要

马约里恩氏溃疡是烧伤瘢痕中的恶性溃疡。恶性肿瘤的类型有鳞状细胞癌、基底细胞癌和恶性黑色素瘤。软组织肉瘤的病例报告仅表明有一种癌症。我们报告了一位 60 多岁的患者,她的左大腿外侧有一个 10 岁的烧伤瘢痕,经活检证实患有鳞状细胞癌,并伴有腹股沟浅表淋巴结转移。我们对左侧进行了广泛切除和溃疡植皮,并进行了髂腹股沟解剖。术后第 12 天,2 天,移植区域附近出现皮下肿胀,活检显示为多形性肉瘤。PET CT 扫描显示左下肢、肝脏和肺部的肌肉有肿瘤沉积。在烧伤瘢痕中同时发生癌和肉瘤的病例报告罕见。报告该病例是因为其罕见性和决策困境。

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本文引用的文献

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Malignant melanoma on a thermal burn scar.热烧伤瘢痕上的恶性黑色素瘤。
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