新生儿阿片类戒断综合征的短期结局：两种方法的比较。
Short term outcomes of neonatal opioid withdrawal syndrome: a comparison of two approaches.
机构信息
Department of Pediatrics, Tufts University School of Medicine, Boston, MA, USA.
Center for Applied Pediatric Quality Analytics, Boston Children's Hospital, Boston, MA, USA.
出版信息
J Perinatol. 2024 Aug;44(8):1137-1145. doi: 10.1038/s41372-024-01953-z. Epub 2024 Apr 2.
OBJECTIVE
To evaluate outcomes in opioid exposed neonates (OENs) assessed by the Eat, Sleep, Console (ESC) tool compared to the Finnegan Neonatal Abstinence Scoring System (FNASS).
METHODS
Retrospective analysis of a statewide database of OENs from 2017 to 2020 with birthing hospitals classified based on the assessment tool used. Four main outcomes were examined using multivariable and Poisson logistic regression models.
RESULTS
Of 2375 OENs, 42.1% received pharmacotherapy (PT) with a consistent decrease in PT, length of treatment (LOT), and length of stay (LOS) over the study period. There was no change in use of mother's own milk (MoM). While outcomes were significantly associated with several specific variables, there were no differences in outcomes between assessment methods.
CONCLUSION
While there was a significant decrease over time in PT, LOT, and LOS, improvements were independent of the assessment tool used and likely related to the increased use of non-pharmacologic care.
目的
通过 Eat, Sleep, Console（ESC）工具评估阿片类药物暴露新生儿（OEN）的结局，并与 Finnegan 新生儿戒断评分系统（FNASS）进行比较。
方法
对 2017 年至 2020 年全州 OEN 的数据库进行回顾性分析，根据使用的评估工具对分娩医院进行分类。使用多变量和泊松逻辑回归模型检查了四个主要结局。
结果
在 2375 名 OEN 中，42.1%接受了药物治疗（PT），PT、治疗时间（LOT）和住院时间（LOS）在研究期间持续下降。母亲自身乳汁（MoM）的使用没有变化。虽然结局与几个特定变量显著相关，但评估方法之间的结局没有差异。
结论
尽管 PT、LOT 和 LOS 随时间显著下降，但改善与评估工具的使用无关，可能与非药物治疗的增加有关。
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