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菲律宾兽用药品的使用:法规、影响、挑战和建议。

Use of veterinary medicinal products in the Philippines: regulations, impact, challenges, and recommendations.

机构信息

The Graduate School, University of Santo Tomas, España Boulevard, Sampaloc, Manila 1008 Metro Manila, Philippines.

Research Center for the Natural and Applied Sciences, University of Santo Tomas, España Boulevard, Sampaloc, Manila 1008 Metro Manila, Philippines.

出版信息

J Vet Sci. 2024 Mar;25(2):e33. doi: 10.4142/jvs.23134.

DOI:10.4142/jvs.23134
PMID:38568834
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10990910/
Abstract

Agricultural production is a major driver of the Philippine economy. Mass production of animal products, such as livestock and poultry farming, is one of the most prominent players in the field. Filipino farmers use veterinary medicinal products (VMPs) when raising agricultural animals to improve animal growth and prevent diseases. Unfortunately, the extensive use of VMPs, particularly antibiotics, has been linked to drug resistance in animals, particularly antibiotics. Antimicrobial gene products produced in animals due to the prolonged use of VMPs can passed on to humans when they consume animal products. This paper reviews information on the use of VMPs in the Philippines, including the regulations, their impact, challenges, and potential recommendations. The Philippines has existing legislation regulating VMP use. Several agencies were tasked to regulate the use of VMPs, such as the Department of Agriculture, the Department of Health, and the Philippine National Action Plan. Unfortunately, there is a challenge to implementing these regulations, which affects consumers. The unregulated use of VMPs influences the transmission of antibiotic residues from animals to crops to humans. This challenge should be addressed, with more focus on stricter regulation.

摘要

农业生产是菲律宾经济的主要驱动力。动物产品的大规模生产,如畜牧业和家禽养殖,是该领域最突出的参与者之一。菲律宾农民在饲养农业动物时使用兽用药品(VMPs)来促进动物生长和预防疾病。不幸的是,VMPs 的广泛使用,特别是抗生素的使用,与动物的耐药性有关,特别是抗生素。由于长期使用 VMPs,动物产生的抗菌基因产物在人类食用动物产品时可能会传递给人类。本文综述了菲律宾 VMP 使用的信息,包括法规、影响、挑战和潜在建议。菲律宾有现有的立法来规范 VMP 的使用。几个机构被赋予监管 VMP 使用的任务,如农业部、卫生部和菲律宾国家行动计划。不幸的是,在执行这些法规方面存在挑战,这影响了消费者。VMP 的不受监管使用影响了抗生素残留从动物到农作物再到人类的传播。应该解决这一挑战,更加注重更严格的监管。

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本文引用的文献

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Antibiotics (Basel). 2021 Apr 9;10(4):410. doi: 10.3390/antibiotics10040410.
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Isolation and molecular characterization of streptococcal species recovered from clinical infections in farmed Nile tilapia (Oreochromis niloticus) in the Philippines.从菲律宾养殖尼罗罗非鱼(尼罗罗非鱼)临床感染中分离出的链球菌种类及其分子特征
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3
Antimicrobials Used in Backyard and Commercial Poultry and Swine Farms in the Philippines: A Qualitative Pilot Study.菲律宾后院及商业家禽和养猪场使用的抗菌药物:一项定性试点研究。
Front Vet Sci. 2020 Jul 8;7:329. doi: 10.3389/fvets.2020.00329. eCollection 2020.
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Multidrug-Resistant Salmonella Serotype Anatum in Travelers and Seafood from Asia, United States.美国旅行者和亚洲海鲜中携带耐多药沙门氏菌血清型 Anatum
Emerg Infect Dis. 2020 May;26(5):1030-1033. doi: 10.3201/eid2605.190992.
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Draft Genome Sequence of Multidrug-Resistant Vibrio parahaemolyticus Strain PH698, Infecting Penaeid Shrimp in the Philippines.感染菲律宾对虾的多重耐药副溶血性弧菌菌株PH698的基因组序列草图
Microbiol Resour Announc. 2019 Nov 21;8(47):e01040-19. doi: 10.1128/MRA.01040-19.
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Microb Drug Resist. 2020 Feb;26(2):160-168. doi: 10.1089/mdr.2019.0019. Epub 2019 Sep 18.
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World Health Organization (WHO) guidelines on use of medically important antimicrobials in food-producing animals.世界卫生组织(WHO)关于在食用动物中使用具有医学重要性的抗菌药物的指南。
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