Wright J T, Gantt D G
Arch Oral Biol. 1985;30(2):201-6. doi: 10.1016/0003-9969(85)90116-5.
Eight primary incisors obtained from a child with dentinogenesis imperfecta (DI) type II were examined histologically using light microscopy and scanning electron microscopy. In both the DI and control teeth, large dentinal canals were observed along the midline of the crown distributed mesial-distally and coursing towards the pulp. Variably-structured mantle dentine was seen in the DI teeth ranging from tubular to virtually atubular. Enamel separation occurred at the dentine-enamel junction despite apparently normal scalloping. In the enamel, fractures occurred along accentuated striae of Retzius where ultrastructurally there was prism bending and discontinuity. The structure of DI teeth probably results from a structural or regulatory protein abnormality and irregular epithelial-mesenchymal interaction. The combined influence of these factors appears to cause variable histologic appearances and rates of tissue deposition.
对取自一名患有II型牙本质发育不全（DI）儿童的八颗乳切牙进行了组织学检查，采用了光学显微镜和扫描电子显微镜。在DI牙齿和对照牙齿中，均观察到沿着牙冠中线分布的大牙本质管，这些牙本质管向近远中方向延伸并通向牙髓。在DI牙齿中可见结构各异的罩牙本质，从管状到几乎无管状。尽管牙本质-釉质界的扇贝状结构看似正常，但仍出现了釉质分离。在釉质中，骨折沿着Retzius线的明显条纹发生，在超微结构上存在棱柱弯曲和不连续性。DI牙齿的结构可能是由结构或调节蛋白异常以及上皮-间充质相互作用不规则导致的。这些因素的综合影响似乎导致了组织学外观和组织沉积速率的变化。
