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宫颈癌的演变格局:通过整合生物技术与人工智能实现筛查与治疗的突破

The Evolving Landscape of Cervical Cancer: Breakthroughs in Screening and Therapy Through Integrating Biotechnology and Artificial Intelligence.

作者信息

Aswathy Raghu, Sumathi Sundaravadivelu

机构信息

Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women, Bharathi Park Rd, Near Forest College Campus, Saibaba Colony, Coimbatore, Tamil Nadu, 641043, India.

出版信息

Mol Biotechnol. 2025 Mar;67(3):925-941. doi: 10.1007/s12033-024-01124-7. Epub 2024 Apr 4.

Abstract

Cervical cancer (CC) continues to be a major worldwide health concern, profoundly impacting the lives of countless females worldwide. In low- and middle-income countries (LMICs), where CC prevalence is high, innovative, and cost-effective approaches for prevention, diagnosis, and treatment are vital. These approaches must ensure high response rates with minimal side effects to improve outcomes. The study aims to compile the latest developments in the field of CC, providing insights into the promising future of CC management along with the research gaps and challenges. Integrating biotechnology and artificial intelligence (AI) holds immense potential to revolutionize CC care, from MobileODT screening to precision medicine and innovative therapies. AI enhances healthcare accuracy and improves patient outcomes, especially in CC screening, where its use has increased over the years, showing promising results. Also, combining newly developed strategies with conventional treatment options presents an optimal approach to address the limitations associated with conventional methods. However, further clinical studies are essential for practically implementing these advancements in society. By leveraging these cutting-edge technologies and approaches, there is a substantial opportunity to reduce the global burden of this preventable malignancy, ultimately improving the lives of women in LMICs and beyond.

摘要

宫颈癌(CC)仍然是全球主要的健康问题,深刻影响着全球无数女性的生活。在宫颈癌患病率较高的低收入和中等收入国家(LMICs),创新且具成本效益的预防、诊断和治疗方法至关重要。这些方法必须确保高响应率且副作用最小,以改善治疗效果。该研究旨在汇总宫颈癌领域的最新进展,深入了解宫颈癌管理的光明未来以及研究差距和挑战。整合生物技术和人工智能(AI)在变革宫颈癌护理方面具有巨大潜力,从移动光学诊断筛查到精准医学和创新疗法。人工智能提高了医疗保健的准确性并改善了患者治疗效果,尤其是在宫颈癌筛查方面,多年来其应用不断增加,显示出令人鼓舞的结果。此外,将新开发的策略与传统治疗方案相结合是解决传统方法相关局限性的最佳途径。然而,进一步的临床研究对于在社会中实际应用这些进展至关重要。通过利用这些前沿技术和方法,有很大机会减轻这种可预防恶性肿瘤的全球负担,最终改善低收入和中等收入国家及其他地区女性的生活。

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