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自发性颅内低血压:临床特征、诊断和治疗策略。

Spontaneous Intracranial Hypotension: Clinical Presentation, Diagnosis, and Treatment Strategies.

机构信息

Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, No. 201, Sec. 2, Shi-Pai Road, Taipei, 11217, Taiwan; Center for Quality Management, Taipei Veterans General Hospital, No. 201, Sec. 2, Shi-Pai Road, Taipei, 11217, Taiwan; College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Shi-Pai Road, Taipei, 11217, Taiwan.

Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, No. 201, Sec. 2, Shi-Pai Road, Taipei, 11217, Taiwan; College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Shi-Pai Road, Taipei, 11217, Taiwan; Brain Research Center, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Shi-Pai Road, Taipei, 11217, Taiwan.

出版信息

Neurol Clin. 2024 May;42(2):473-486. doi: 10.1016/j.ncl.2024.02.002. Epub 2024 Feb 28.

Abstract

Spontaneous intracranial hypotension (SIH) typically presents as an acute orthostatic headache during an upright position, secondary to spinal cerebrospinal fluid leaks. New evidence indicates that a lumbar puncture may not be essential for diagnosing every patient with SIH. Spinal neuroimaging protocols used for diagnosing and localizing spinal cerebrospinal fluid leaks include brain/spinal MRI, computed tomography myelography, digital subtraction myelography, and radionuclide cisternography. Complications of SIH include subdural hematoma, cerebral venous thrombosis, and superficial siderosis. Treatment options encompass conservative management, epidural blood patches, and surgical interventions. The early application of epidural blood patches in all patients with SIH is suggested.

摘要

自发性颅内低血压(SIH)通常在直立时表现为急性直立性头痛,继发于脊柱脑脊液漏。新的证据表明,腰椎穿刺对于诊断每个 SIH 患者并非必不可少。用于诊断和定位脊柱脑脊液漏的脊柱神经影像学方案包括脑/脊髓 MRI、计算机断层脊髓造影、数字减影脊髓造影和放射性核素脑池造影。SIH 的并发症包括硬膜下血肿、脑静脉血栓形成和脑表铁沉积症。治疗方案包括保守治疗、硬膜外血贴和手术干预。建议对所有 SIH 患者早期应用硬膜外血贴。

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