Ma Mingshen, Liu Rui, Li Jing, Yang Hang, Yang Runzi, Ma Jianmin
Department of Ophthalmology, Beijing Chaoyang Hospital, Capital Medical University, 100027, Beijing, China.
Department of Ophthalmology, School of Medicine, Stanford University, Palo Alto, CA, 94301, United States.
Heliyon. 2024 Mar 26;10(7):e28511. doi: 10.1016/j.heliyon.2024.e28511. eCollection 2024 Apr 15.
Sebaceous gland hyperplasia of the eyelids, known as adenomatoid or pseudoadenomatous hyperplasia, is a rare benign condition. Optimal management strategies for this specific type of eyelid tumor require further investigation.
The patient presented with a 21-year history of a progressively enlarged mass in the right lower eyelid. Previous treatments, including laser photocoagulation and surgical excision, have failed to prevent recurrence. The mass, characterized by a firm texture and low mobility, has raised concerns regarding malignancy. However, histopathological examination following surgical excision identified the mass as sebaceous gland hyperplasia. The patient's medical history was notable for benign gastrointestinal and intestinal polyps with no evidence of malignancy.
A final diagnosis of eyelid sebaceous gland hyperplasia was established after surgical excision and comprehensive histopathological analyses. The patient's successful recovery without recurrence over a three-month follow-up period post-surgery highlights the efficacy of the surgical approach and the use of intraoperative frozen section pathological examination.
眼睑皮脂腺增生，又称腺瘤样或假腺瘤样增生，是一种罕见的良性疾病。针对这种特定类型眼睑肿瘤的最佳治疗策略需要进一步研究。
患者右下眼睑肿物渐进性增大21年。既往治疗，包括激光光凝和手术切除，均未能防止复发。肿物质地硬、活动度低，引发了对恶性肿瘤的担忧。然而，手术切除后的组织病理学检查确定肿物为皮脂腺增生。患者有良性胃肠道和肠道息肉病史，无恶性肿瘤证据。
手术切除及全面的组织病理学分析后确诊为眼睑皮脂腺增生。患者术后三个月随访成功康复且无复发，突出了手术方法及术中冰冻切片病理检查的有效性。
