卡佩萨布罗利德A，一种来自于……的具有抗炎活性的新型杂萜类化合物。 （你提供的原文似乎不完整，“from”后面缺少具体来源信息）
Carpesabrolide A, a novel meroterpenoid with anti-inflammatory activity from .
作者信息
Zhang Xiao-Fang, Du Jiao-Xian, Teng Si-Qiong, Liu Hui, He Juan, Feng Tao, Liu Ji-Kai
机构信息
School of Pharmaceutical Sciences, South-Central Minzu University 182 Minzu Road Wuhan 430074 P.R. China
National Demonstration Center for Experimental Ethnopharmacology Education, South-Central Minzu University Wuhan 430074 China.
出版信息
RSC Adv. 2024 Apr 5;14(16):11002-11006. doi: 10.1039/d4ra00292j. eCollection 2024 Apr 3.
Carpesabrolide A (1), featuring an unprecedented fumaric acid-guaiane sesquiterpenoid hybrid, has been isolated from the folk medicinal plant . The structure with absolute configuration has been established by spectroscopic methods and single crystal X-ray diffraction analysis. The plausible biosynthetic pathway for 1 is proposed. Compound 1 shows significant anti-inflammatory activity by inhibiting NO production with an IC value of 2.7 μM.
卡佩沙布罗利德A（1）是一种前所未有的富马酸-愈创木烷倍半萜杂合体，已从一种民间药用植物中分离出来。其具有绝对构型的结构已通过光谱方法和单晶X射线衍射分析得以确定。还提出了化合物1可能的生物合成途径。化合物1通过抑制一氧化氮生成显示出显著的抗炎活性，其半数抑制浓度值为2.7 μM。
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