The calculation of statistical power has been taken up as a simple yet informative tool to assist in designing an experiment, particularly in justifying sample size. A difficulty with using power for this purpose is that the classical power formula does not incorporate sources of uncertainty (e.g., sampling variability) that can impact the computed power value, leading to a false sense of precision and confidence in design choices. We use simulations to demonstrate the consequences of adding two common sources of uncertainty to the calculation of power. Sampling variability in the estimated effect size (Cohen's ) can introduce a large amount of uncertainty (e.g., sometimes producing rather flat distributions) in power and sample-size determination. The addition of random fluctuations in the population effect size can cause values of its estimates to take on a sign opposite the population value, making calculated power values meaningless. These results suggest that calculated power values or use of such values to justify sample size add little to planning a study. As a result, researchers should put little confidence in power-based choices when planning future studies. (PsycInfo Database Record (c) 2024 APA, all rights reserved).