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儿科慢性疼痛分级:修订后的儿科慢性疼痛严重程度分类。

Pediatric chronic pain grading: a revised classification of the severity of pediatric chronic pain.

机构信息

German Paediatric Pain Centre, Children's and Adolescents' Hospital, Datteln, Germany.

Department of Children's Pain Therapy and Paediatric Palliative Care, Faculty of Health, School of Medicine, Witten/Herdecke University, Witten, Germany.

出版信息

Pain. 2024 Sep 1;165(9):2087-2097. doi: 10.1097/j.pain.0000000000003226. Epub 2024 Apr 5.

Abstract

In this study, we describe the development and validation of a revised Pediatric Chronic Pain Grading (P-CPG) for children aged 8 to 17 years that adds emotional impairment to previously used measures of pain intensity and functional impairment. Such a measure enables the assessment of chronic pain severity in different epidemiological and clinical populations, the stratification of treatment according to pain severity, and the monitoring of treatment outcome. The P-CPG was developed using a representative sample of school children with chronic pain (n = 454; M age = 12.95, SD = 2.22). Construct validity and sensitivity to change were examined within a sample of N = 2448 children and adolescents (M age = 12.71, SD = 2.47) comprising 3 subsamples (school n = 1562, primary care n = 129, and tertiary care n = 757) affected by chronic pain to varying extents. Results showed that P-CPG grades differed significantly among the 3 subsamples, with school children being least affected by chronic pain and tertiary care patients being most affected. As P-CPG grade increased, so did pain intensity, functional impairment, pain-related school absence, and emotional impairment. Convergent validity was demonstrated by significant positive correlations between the P-CPG and global ratings of pain severity as well as objective claims data; the latter reflects greater health care costs with increasing P-CPG scores. Sensitivity to change was supported by a significant reduction in baseline P-CPG grades 3 and 6 months after intensive interdisciplinary pain treatment in tertiary care sample. In conclusion, the P-CPG is an appropriate measure of pain severity in children and adolescents with chronic pain in clinical as well as epidemiological settings.

摘要

在这项研究中,我们描述了一种修订后的儿科慢性疼痛分级(P-CPG)的开发和验证,该分级针对 8 至 17 岁的儿童,在以前用于衡量疼痛强度和功能障碍的措施中增加了情感障碍。这样的衡量标准可以评估不同流行病学和临床人群中的慢性疼痛严重程度,根据疼痛严重程度进行治疗分层,并监测治疗效果。P-CPG 的开发使用了一个具有代表性的患有慢性疼痛的学龄儿童样本(n=454;M 年龄=12.95,SD=2.22)。在一个由 2448 名儿童和青少年(M 年龄=12.71,SD=2.47)组成的样本中,对其进行了结构效度和变化敏感性的检验,该样本包含了 3 个亚组(学校 n=1562,初级保健 n=129,三级保健 n=757),他们受到慢性疼痛的影响程度不同。结果表明,在这 3 个亚组中,P-CPG 分级有显著差异,学校儿童受慢性疼痛的影响最小,而三级保健患者受影响最大。随着 P-CPG 分级的增加,疼痛强度、功能障碍、与疼痛相关的缺课以及情感障碍也随之增加。P-CPG 与疼痛严重程度的总体评价以及客观索赔数据之间存在显著的正相关,这证明了其具有良好的收敛效度;后者反映了随着 P-CPG 评分的增加,医疗保健成本的增加。在三级保健样本中,经过强化的跨学科疼痛治疗后,基线 P-CPG 分级在 3 个月和 6 个月时显著降低,这支持了其具有良好的变化敏感性。总之,P-CPG 是评估临床和流行病学环境中患有慢性疼痛的儿童和青少年疼痛严重程度的一种合适的衡量标准。

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