Piran N, Kennedy S, Garfinkel P E, Owens M
J Nerv Ment Dis. 1985 Jul;173(7):395-400. doi: 10.1097/00005053-198507000-00002.
Thirty-three bulimic and 14 restrictive anorexics were compared on DSM-III diagnoses of affective and anxiety disorders, observer-rated and self-rated measures of depression and anxiety, and family history. A subgroup of 18 eating disorder subjects was administered the dexamethasone suppression test. The same 18 subjects were compared to 13 subjects with affective disorder on the Schedule for Affective Disorders and Schizophrenia. It was found that a large group with bulimia and restrictive anorexia nervosa was subject to a depressive disorder. Thirty-eight percent of the sample fulfilled criteria for a major depressive episode. The dysphoric experience seemed as intense in the bulimic and restricter group. There was a high incidence of dexamethasone nonsuppression (55%), which was found to be related to various measures of depression. Bulimics and restricters differed in their family history of affective disorder. While 61% of bulimics had a positive history of depression, this was found in only 23% of restricters (p less than .03).
对33名暴食症患者和14名限制型厌食症患者进行了比较，比较内容包括《精神疾病诊断与统计手册》第三版（DSM-III）中情感障碍和焦虑症的诊断、观察者评定和自我评定的抑郁与焦虑量表，以及家族史。对18名饮食失调受试者亚组进行了地塞米松抑制试验。将这18名受试者与13名情感障碍患者在《情感障碍与精神分裂症日程表》上进行了比较。结果发现，一大组患有暴食症和限制型神经性厌食症的患者患有抑郁症。38%的样本符合重度抑郁发作的标准。暴食症和限制型患者组的烦躁体验似乎同样强烈。地塞米松不抑制的发生率很高（55%），且发现其与各种抑郁量表相关。暴食症患者和限制型患者在情感障碍家族史上存在差异。虽然61%的暴食症患者有抑郁症阳性家族史，但限制型患者中只有23%有此情况（p小于0.03）。
