了解新冠病毒感染后出现长期影响的成年幸存者所使用的患者报告结局指标：一项快速综述
Understanding Patient-Reported Outcome Measures Used in Adult Survivors Experiencing Long-Term Effects After COVID-19 Infection: A Rapid Review.
作者信息
Barilaite Egle, Watson Harry, Hocaoglu Mevhibe B
机构信息
Cicely Saunders Institute of Palliative Care, Policy & Rehabilitation, King's College London, London, United Kingdom.
出版信息
J Patient Cent Res Rev. 2024 Apr 2;11(1):36-50. doi: 10.17294/2330-0698.2041. eCollection 2024 Spring.
PURPOSE
Patient-reported outcome measures (PROMs) are used in individuals experiencing long-term effects from COVID-19 infection, or Long COVID, to evaluate the quality of life and functional status of these individuals. However, little is known about which PROMs are being utilised and the psychometric properties of these PROMs. Our purpose was thus to explore which PROMs are used in Long COVID patients and to discuss the psychometric properties of the PROMs.
METHODS
For this rapid review, a systematic literature search was performed in the PubMed, Embase, and CINAHL databases. The found studies were screened using the PRISMA flowchart. We then performed study quality appraisal and assessed the psychometric properties of the found PROMs.
RESULTS
Per the systematic literature search and after removal of duplicates, 157 publications were identified for individual screening. After screening and eligibility assessment, 74 articles were selected for our review. In total, 74 PROMs were used and primarily comprised quality of life, fatigue, breathlessness, mental health, and smell/taste issues in COVID "long haulers." Five studies used newly developed, COVID-19-specific PROMs. We assessed the psychometric properties of the 10 most-used PROMs. The majority were found to be reliable and valid instruments. EQ-5D-5L was the most popular and highly rated PROM.
CONCLUSIONS
We assessed PROMs used in Long COVID patients and evaluated their psychometric properties. EQ-5D-5L was the most favourably rated PROM. PROMs addressing mental health issues are crucial in managing anxiety and depression in Long COVID patients. New COVID-specific PROMs assess functional status and smell/taste perception and show great utilisation potential in olfactory training at COVID smell clinics. However, many reviewed PROMs currently lack sufficient analysis of their psychometric properties. Therefore, future research needs to examine these measures.
目的
患者报告结局测量指标（PROMs）用于评估感染新冠病毒后出现长期影响（即“长新冠”）的个体的生活质量和功能状态。然而，对于正在使用哪些PROMs以及这些PROMs的心理测量特性，人们知之甚少。因此，我们的目的是探究“长新冠”患者使用了哪些PROMs，并讨论这些PROMs的心理测量特性。
方法
为进行这项快速综述，我们在PubMed、Embase和CINAHL数据库中进行了系统的文献检索。使用PRISMA流程图对检索到的研究进行筛选。然后我们进行了研究质量评估，并评估了所发现的PROMs的心理测量特性。
结果
通过系统的文献检索并去除重复文献后，共识别出157篇出版物以供逐一筛选。经过筛选和资格评估，我们选择了74篇文章进行综述。总共使用了74种PROMs，主要包括“长新冠”患者的生活质量、疲劳、呼吸急促、心理健康以及嗅觉/味觉问题。五项研究使用了新开发的、针对新冠病毒的PROMs。我们评估了10种使用最频繁的PROMs的心理测量特性。发现大多数都是可靠且有效的工具。EQ-5D-5L是最受欢迎且评分很高的PROM。
结论
我们评估了“长新冠”患者使用的PROMs，并评估了它们的心理测量特性。EQ-5D-5L是评分最有利的PROM。解决心理健康问题的PROMs对于管理“长新冠”患者的焦虑和抑郁至关重要。新的针对新冠病毒的PROMs可评估功能状态和嗅觉/味觉感知，在新冠嗅觉诊所的嗅觉训练中显示出巨大的应用潜力。然而，许多综述中的PROMs目前对其心理测量特性缺乏充分分析。因此，未来的研究需要对这些测量指标进行检验。
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