Schmid E, Kornman K S, Tinanoff N
J Periodontol. 1985 Jun;56(6):330-3. doi: 10.1902/jop.1985.56.6.330.
Periodontal pockets of 11 subjects were irrigated once with either 1.64% SnF2 or saline applied by syringe. Changes on the total anaerobic colony forming units (CFU) and black pigmented bacteroides (BPBs) of the irrigated pockets were assessed for 31 days. The results showed little change of the CFUs by either single application of SnF2 or saline. However, SnF2 irrigation produced a decrease in the BPBs for 1 week with the greatest effect (1/2 log reduction) being seen at 3 days after the irrigation. Some subjects had more impressive reductions in BPBs, yet four of the 11 subjects showed no reductions in BPBs in those sites irrigated with SnF2. Further studies with frequent irrigation intervals are necessary to evaluate the potential usefulness of SnF2 for subgingival irrigation.
用注射器向11名受试者的牙周袋分别冲洗一次1.64%的氟化亚锡或生理盐水。在31天内评估冲洗后牙周袋中总厌氧菌集落形成单位（CFU）和产黑色素类杆菌（BPB）的变化。结果显示，单次应用氟化亚锡或生理盐水后，CFU变化不大。然而，氟化亚锡冲洗使BPB在1周内减少，冲洗后3天效果最显著（减少1/2对数）。一些受试者的BPB减少更为明显，但11名受试者中有4名在用氟化亚锡冲洗的部位BPB没有减少。需要进一步研究频繁冲洗间隔，以评估氟化亚锡用于龈下冲洗的潜在效用。
