Dharma Vira Heart Center Sir Ganga Ram Hospital, New Delhi, 110060, India.
Indian Heart J. 2024 Mar;76 Suppl 1(Suppl 1):S73-S74. doi: 10.1016/j.ihj.2023.11.270. Epub 2024 Apr 8.
Evidence from the existing literature suggests that exercise has positive effects for prevention and treatment of cardiovascular diseases by reducing risk factors such as elevated blood lipids. Based on clinical and observational clinical trials, it is well established that increased physical activity and regular exercise has a favourable impact on blood lipids and lipoprotein profiles. Exercise training significantly decreases blood triglycerides concentration and increases high density lipoprotein cholesterol levels. Though the Indian data depicting the effect of exercise on lipids is scarce, exercise directly improves "atherogenic dyslipidaemia" which is frequently present among Indians i.e. HDL-C is increased, TG is reduced and LDL-C particle size is improved. While drug therapy is key to the treatment of dyslipidaemia, lifestyle alterations such as exercise should continue to be actively promoted and encouraged by clinicians. Exercise is a low cost, non pharmacological therapeutic lifestyle change that is of value to lipid metabolism and cardiovascular fitness.
现有文献证据表明,运动通过降低血脂升高等风险因素对心血管疾病的预防和治疗有积极影响。基于临床和观察性临床试验,越来越多的身体活动和规律运动对血脂和脂蛋白谱有有利影响已得到充分证实。运动训练可显著降低血三酰甘油浓度并增加高密度脂蛋白胆固醇水平。虽然印度的数据描绘了运动对血脂的影响,但运动直接改善了“动脉粥样硬化性血脂异常”,这在印度人中很常见,即 HDL-C 升高,TG 降低,LDL-C 颗粒大小改善。虽然药物治疗是治疗血脂异常的关键,但临床医生应继续积极提倡和鼓励改变生活方式,如运动。运动是一种低成本、非药物的治疗性生活方式改变,对脂质代谢和心血管健康有益。