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多发性骨髓瘤患者的疼痛管理：文献综述

Pain Management in Multiple Myeloma Patients: A Literature Review.

作者信息

Rana Shubh, Maharjan Suprina, Sookdeo Shanisha D, Schmidt Patrik

机构信息

Cardiology, Maimonides Medical Center, Brooklyn, USA.

Internal Medicine, Xavier University School of Medicine, Oranjestad, ABW.

出版信息

Cureus. 2024 Mar 11;16(3):e55975. doi: 10.7759/cureus.55975. eCollection 2024 Mar.

DOI:10.7759/cureus.55975
PMID:38601412
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11006436/
Abstract

Managing pain in cancer patients with multiple myeloma (MM) poses a considerable challenge. This review thoroughly investigates current pain management strategies, difficulties, and future directions in the field. The review divides pain treatment strategies into pharmaceutical and non-pharmacological therapies. Looking ahead, promising areas for future study and development are mentioned, such as incorporating precision medicine into pain management and investigating innovative therapeutics. Despite existing limitations, advances in pain management provide great opportunities to improve the quality of life and overall results for MM patients.

摘要

对多发性骨髓瘤（MM）癌症患者进行疼痛管理是一项颇具挑战的任务。本综述全面调查了该领域当前的疼痛管理策略、困难及未来方向。综述将疼痛治疗策略分为药物治疗和非药物治疗。展望未来，提到了未来研究和发展的有前景的领域，如将精准医学纳入疼痛管理以及研究创新疗法。尽管存在现有局限性，但疼痛管理的进展为提高MM患者的生活质量和总体疗效提供了巨大机遇。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ffd/11006436/9d2fa9721453/cureus-0016-00000055975-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ffd/11006436/4f39d3a6c315/cureus-0016-00000055975-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ffd/11006436/9d2fa9721453/cureus-0016-00000055975-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ffd/11006436/4f39d3a6c315/cureus-0016-00000055975-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ffd/11006436/9d2fa9721453/cureus-0016-00000055975-i02.jpg

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本文引用的文献

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Data gaps and opportunities for modeling cancer health equity.癌症健康公平性建模的数据差距和机会。
J Natl Cancer Inst Monogr. 2023 Nov 8;2023(62):246-254. doi: 10.1093/jncimonographs/lgad025.
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Assessment tools for patient-reported outcomes in multiple myeloma.多发性骨髓瘤患者报告结局评估工具。
Support Care Cancer. 2023 Jun 30;31(7):431. doi: 10.1007/s00520-023-07902-4.
3
The core symptom in multiple myeloma patients undergoing chemotherapy: a network analysis.化疗后多发性骨髓瘤患者的核心症状：网络分析。
Support Care Cancer. 2023 Apr 25;31(5):297. doi: 10.1007/s00520-023-07759-7.
4
Survey of patients and physicians on shared decision-making in treatment selection in relapsed/refractory multiple myeloma.复发/难治性多发性骨髓瘤患者和医生在治疗选择中共同决策的调查。
Transl Behav Med. 2023 Apr 15;13(4):255-267. doi: 10.1093/tbm/ibac099.
5
Pain as a risk factor of depression and anxiety symptoms with multiple myeloma during maintenance therapy.疼痛作为维持治疗期间多发性骨髓瘤患者抑郁和焦虑症状的风险因素。
Front Psychol. 2022 Nov 30;13:1015497. doi: 10.3389/fpsyg.2022.1015497. eCollection 2022.
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A systematic review and meta-analysis of interventional studies of bisphosphonates and denosumab in multiple myeloma and future perspectives.双膦酸盐和地舒单抗治疗多发性骨髓瘤的介入性研究的系统评价和荟萃分析及未来展望。
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Multiple Myeloma Therapy: Emerging Trends and Challenges.多发性骨髓瘤治疗：新趋势与挑战
Cancers (Basel). 2022 Aug 23;14(17):4082. doi: 10.3390/cancers14174082.
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Patient perspectives on symptoms, health-related quality of life, and treatment experience associated with relapsed/refractory multiple myeloma.患者对复发/难治性多发性骨髓瘤相关症状、健康相关生活质量和治疗体验的看法。
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