Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Villa Roberto Edoardo, Woutersen Ruud, Herman Lieve, Galobart Jaume, Holczknecht Orsolya, Innocenti Matteo, Ortuño Jordi, Pettenati Elisa, Pizzo Fabiola, Revez Joana, Tarrés-Call Jordi, Vettori Maria Vittoria, Radovnikovic Anita
EFSA J. 2024 Apr 10;22(4):e8627. doi: 10.2903/j.efsa.2024.8627. eCollection 2024 Apr.
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of the selenised yeast (inactivated) CCTCC M 2022402 (Plexomin® Se 3000, available in two forms: 'granules' and 'micro') as a nutritional feed additive for all animal species. Based on a tolerance-efficacy trial, the FEEDAP Panel concluded that the additive is safe for chickens for fattening at proposed conditions of use and this conclusion can be extrapolated to all animal species. In the absence of deposition data in all animal species and products, the FEEDAP Panel cannot conclude on the safety for the consumer. Plexomin® Se 3000 (granules) is dust-free; therefore, the exposure through inhalation is unlikely. Plexomin® Se 3000 (micro) presents a risk by inhalation. Both forms of the additive (granules and micro) are considered as respiratory sensitisers. Due to the lack of data, no conclusions can be drawn on the dermal and eye irritation potential of Plexomin® Se 3000 (granules). Plexomin® Se 3000 (micro) is not irritant to the skin and the eyes. No conclusions can be drawn on the potential of both forms of the additive to be dermal sensitisers. The use of the additive in animal nutrition is considered safe for the environment. The additive is an efficacious source of selenium in feedingstuffs for all animal species.
应欧盟委员会的要求，欧洲食品安全局（EFSA）被要求就硒化酵母（灭活）CCTCC M 2022402（Plexomin® Se 3000，有“颗粒”和“微粒”两种形式）作为所有动物物种的营养饲料添加剂的安全性和有效性发表科学意见。基于一项耐受性-功效试验，饲料添加剂和动物产品营养小组得出结论，在所提议的使用条件下，该添加剂对育肥鸡是安全的，这一结论可外推至所有动物物种。由于缺乏所有动物物种及其产品中的沉积数据，饲料添加剂和动物产品营养小组无法就其对消费者的安全性得出结论。Plexomin® Se 3000（颗粒）无粉尘；因此，通过吸入途径的接触不太可能发生。Plexomin® Se 3000（微粒）存在吸入风险。该添加剂的两种形式（颗粒和微粒）均被视为呼吸道致敏剂。由于缺乏数据，无法就Plexomin® Se 3000（颗粒）的皮肤和眼睛刺激潜力得出结论。Plexomin® Se 3000（微粒）对皮肤和眼睛无刺激性。无法就该添加剂两种形式作为皮肤致敏剂的潜力得出结论。该添加剂在动物营养中的使用被认为对环境是安全的。该添加剂是所有动物物种饲料中有效的硒来源。
