伴有骨髓嗜酸性粒细胞增多及16号染色体结构异常的急性非淋巴细胞白血病
Acute nonlymphoblastic leukemia with bone marrow eosinophilia and structural anomaly of chromosome 16.
作者信息
Mecucci C, Bosly A, Michaux J L, Broeckaert-Van Orshoven A, Van den Berghe H
出版信息
Cancer Genet Cytogenet. 1985 Aug;17(4):359-63. doi: 10.1016/0165-4608(85)90120-7.
PMID:3860282
Abstract
A patient with acute myelocytic leukemia in relapse presented with t(16;21) (p12;q22). Hematologic studies revealed a large number of abnormal eosinophils in the bone marrow. The complexity of chromosome #16 rearrangements associated with acute nonlymphocytic leukemia and the possible significance of chromosomes #16 and #21 in relation to the concomitant eosinophilia are briefly discussed.
摘要
一名复发的急性髓细胞白血病患者呈现出t(16;21) (p12;q22)。血液学研究显示骨髓中有大量异常嗜酸性粒细胞。本文简要讨论了与急性非淋巴细胞白血病相关的16号染色体重排的复杂性以及16号和21号染色体与伴随的嗜酸性粒细胞增多可能的相关性。
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