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原发性打鼾成人睡眠磨牙症的患病率及相关因素:一项大规模多导睡眠图研究。

Prevalence and risk factors of sleep bruxism in adults with primary snoring: a large-scale polysomnographic study.

机构信息

Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Department of Clinical Neurophysiology, OLVG West, Amsterdam, The Netherlands.

出版信息

J Clin Sleep Med. 2024 Aug 1;20(8):1331-1337. doi: 10.5664/jcsm.11142.

Abstract

STUDY OBJECTIVES

To determine the prevalence and risk factors of sleep bruxism (SB) in adults with primary snoring (PS).

METHODS

This study included 292 adults with PS (140 males, 152 females; mean age ± standard deviation = 42.8 ± 12.2 years; mean body mass index ± standard deviation = 26.7 ± 4.7 kg/m) without previous treatment for snoring. SB was diagnosed based on the frequency of the biomarker of SB: rhythmic masticatory muscle activity (SB when rhythmic masticatory muscle activity ≥ 2 episodes/h). Logistic regression was performed, with SB as the dependent variable and with age, sex, body mass index, and sleep- and respiratory-related polysomnographic parameters as the independent variables to identify the risk factors for SB.

RESULTS

The prevalence of SB was 44.6% in adults with PS. Younger age (odds ratio = 0.965 [0.944, 0.987]) and shorter total sleep time (odds ratio = 0.760 [0.609, 0.948]) significantly increased the risk of SB ( < .05).

CONCLUSIONS

SB is highly prevalent in adults with PS. Younger age and shorter sleep time are significant risk factors for SB in adults with PS.

CLINICAL TRIAL REGISTRATION

Registry: onderzoekmetmensen.nl; Name: A Large Sample Polysomnographic Study on Sleep Bruxism; URL: https://trialsearch.who.int/Trial2.aspx?TrialID=NL-OMON19947; Identifier: NL8516.

CITATION

Li D, Lobbezoo F, Hilgevoord AAJ, de Vries N, Aarab G. Prevalence and risk factors of sleep bruxism in adults with primary snoring: a large-scale polysomnographic study. . 2024;20(8):1331-1337.

摘要

研究目的

确定原发性打鼾(PS)成年人中睡眠磨牙症(SB)的患病率和危险因素。

方法

本研究纳入了 292 名未经打鼾治疗的原发性打鼾成年人(140 名男性,152 名女性;平均年龄±标准差=42.8±12.2 岁;平均体重指数±标准差=26.7±4.7 kg/m)。根据 SB 的生物标志物——节律性咀嚼肌活动(节律性咀嚼肌活动≥2 次/小时时为 SB)来诊断 SB。采用 logistic 回归分析,以 SB 为因变量,以年龄、性别、体重指数和睡眠及呼吸相关多导睡眠图参数为自变量,确定 SB 的危险因素。

结果

PS 成年人中 SB 的患病率为 44.6%。年龄较小(比值比=0.965[0.944, 0.987])和总睡眠时间较短(比值比=0.760[0.609, 0.948])显著增加了 SB 的风险(<0.05)。

结论

PS 成年人中 SB 的患病率很高。年龄较小和睡眠时间较短是 PS 成年人发生 SB 的显著危险因素。

临床试验注册

研究人员注册库:onderzoekmetmensen.nl;研究名称:一项关于睡眠磨牙症的大型多导睡眠图研究;网址:https://trialsearch.who.int/Trial2.aspx?TrialID=NL-OMON19947;标识符:NL8516。

引文

Li D, Lobbezoo F, Hilgevoord AAJ, de Vries N, Aarab G. 原发性打鼾成年人睡眠磨牙症的患病率和危险因素:一项大型多导睡眠图研究。睡眠医学杂志。2024;20(8):1331-1337.

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