Int J Oral Maxillofac Implants. 2024 Aug 29;39(4):506-515. doi: 10.11607/jomi.10600.
To assess histologic and imaging outcomes related to new bone formation around implants, inserted simultaneously with sinus augmentation, and compare different types of grafts.
This systematic review (SR) was carried out following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and the Cochrane Handbook for Systematic Reviews of Interventions. LILACS/BVS, MEDLINE/PubMed, Cochrane Library, and Embase databases, including gray literature and manual investigations, were searched to identify clinical trials reporting specific requirements. The present study needed human histologic and imaging data of bone formation around implants inserted into the maxillary sinus simultaneously with elevation and augmentation procedures. Study selection, risk of bias (Rob 2.0 or ROBINS-I), quality of evidence (GRADE), and data collection were performed by two independent reviewers.
Of the 1,101 potentially eligible articles, 44 were retrieved, 12 were assessed for eligibility, and 5 were included (4 randomized and 1 controlled clinical trial). As a result, 130 grafted sinuses with 179 placed implants in 103 patients were analyzed. The patients were aged between 24 and 79 years and followed up between 6 and 15 months. The heterogeneity between studies did not allow the data to be combined for meta-analysis. All graft materials proved to be viable options for the intervention. The use of biphasic calcium phosphate was related to higher bone-to-implant contact.
All of the assessed grafts are viable options for the addressed intervention. The use of some material is justified to maintain the sinus volume and allow bone formation in the apical implant site under the sinus membrane. Longer chair time and donor site morbidity should be considered when choosing autogenous bone. Synthetic biphasic materials can be selected for this intervention due to superior bone-to-implant contact compared to deproteinized bovine bone.
评估与同期窦提升和窦腔增大植入物周围新骨形成相关的组织学和影像学结果，并比较不同类型的移植物。
本系统评价（SR）遵循系统评价和荟萃分析的首选报告项目（PRISMA）和 Cochrane 干预系统评价手册进行。对 LILACS/BVS、MEDLINE/PubMed、Cochrane 图书馆和 Embase 数据库进行了搜索，包括灰色文献和手工调查，以确定报告特定要求的临床研究。本研究需要人类组织学和影像学数据，以评估同时进行上颌窦提升和增大手术时植入物周围的骨形成。研究选择、偏倚风险（Rob 2.0 或 ROBINS-I）、证据质量（GRADE）和数据收集由两名独立的审查员进行。
从 1101 篇潜在合格文章中，检索到 44 篇，评估了 12 篇文章的合格性，最终纳入 5 篇文章（4 项随机对照临床试验和 1 项对照临床试验）。因此，分析了 103 名患者的 130 个移植窦和 179 个植入物。患者年龄在 24 至 79 岁之间，随访时间为 6 至 15 个月。研究之间的异质性不允许对数据进行合并进行荟萃分析。所有移植物材料均被证明是该干预措施的可行选择。双相磷酸钙的使用与更高的骨-种植体接触率相关。
所有评估的移植物都是该干预措施的可行选择。使用某些材料可以维持窦腔体积，并允许在窦膜下的根尖种植部位形成骨。在选择自体骨时，应考虑更长的椅旁时间和供区并发症。与脱蛋白牛骨相比，合成双相材料可用于该干预措施，因为其具有更高的骨-种植体接触率。
