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通过健康的生活方式增强免疫力:COVID-19管理中生活方式干预的建议。

Strengthening immunity through healthy lifestyle practices: Recommendations for lifestyle interventions in the management of COVID-19.

作者信息

Monye Ifeoma, Adelowo Abiodun Bamidele

机构信息

Department of Family Medicine National Hospital Abuja Nigeria.

Brookfield Centre for Lifestyle Medicine Abuja Nigeria.

出版信息

Lifestyle Med (Hoboken). 2020 Jul;1(1):e7. doi: 10.1002/lim2.7. Epub 2020 Oct 3.

DOI:10.1002/lim2.7
PMID:38607804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7646052/
Abstract

Although the practice of strengthening the immune system may not guarantee that people will not contract severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is evidence that suggests that the likelihood and severity of many viral infections can be considerably reduced if appropriate measures are taken to increase the efficacy of the immune response to invading organisms. Evidence-based public health measures to reduce viral spread include-personal isolation, physical distancing, wearing facial masks, frequent hand washing with soap and running water, not touching the face, vaccination, etc. However once infected, recovery relies on host immunity to eradicate the foreign invaders, with symptomatic management, which is the core management strategy in COVID-19 management guidelines. Researchers have observed that severe COVID-19 prevalence and mortality is highest in people with preexisting conditions. Eighty percent of these preexisting diseases are lifestyle related. Also, the science of strengthening the immune system by adopting appropriate lifestyle changes is still evolving, especially among the suspected and confirmed COVID-19 cases. This article briefly highlights the immune response to viral infections including COVID-19 and refers to evidence that healthy lifestyle practices, enshrined as core aspects of lifestyle medicine, can strengthen the immune response to infections. This may improve outcome in COVID-19. We therefore recommend specific evidence-based lifestyle intervention measures that should be considered in the management of COVID-19.

摘要

虽然增强免疫系统的做法可能无法保证人们不会感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2),但有证据表明,如果采取适当措施提高对入侵生物体的免疫反应效力,许多病毒感染的可能性和严重程度会大幅降低。基于证据的减少病毒传播的公共卫生措施包括——个人隔离、保持社交距离、佩戴口罩、用肥皂和流水勤洗手、不触摸面部、接种疫苗等。然而,一旦感染,康复依赖于宿主免疫力来清除外来入侵者,并进行症状管理,这是新冠疫情管理指南中的核心管理策略。研究人员观察到,已有疾病患者的重症新冠患病率和死亡率最高。这些已有疾病中有80%与生活方式有关。此外,通过采取适当的生活方式改变来增强免疫系统的科学仍在不断发展,尤其是在疑似和确诊的新冠病例中。本文简要介绍了包括新冠病毒感染在内的对病毒感染的免疫反应,并提及有证据表明,作为生活方式医学核心内容的健康生活方式可以增强对感染的免疫反应。这可能改善新冠患者的预后。因此,我们推荐在新冠疫情管理中应考虑的基于证据的具体生活方式干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73e7/7646052/b1eae69b4c8c/LIM2-1-e7-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73e7/7646052/e9d421d6aeb7/LIM2-1-e7-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73e7/7646052/b1eae69b4c8c/LIM2-1-e7-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73e7/7646052/e9d421d6aeb7/LIM2-1-e7-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73e7/7646052/b1eae69b4c8c/LIM2-1-e7-g004.jpg

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