• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

利用生成式人工智能进行临床证据综合需要确保其可信度。

Leveraging generative AI for clinical evidence synthesis needs to ensure trustworthiness.

机构信息

Columbia University, Department of Biomedical Informatics, New York, 10032, USA.

National Institutes of Health, National Library of Medicine, National Center for Biotechnology Information, Bethesda, 20894, USA.

出版信息

J Biomed Inform. 2024 May;153:104640. doi: 10.1016/j.jbi.2024.104640. Epub 2024 Apr 10.

DOI:10.1016/j.jbi.2024.104640
PMID:38608915
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11217921/
Abstract

Evidence-based medicine promises to improve the quality of healthcare by empowering medical decisions and practices with the best available evidence. The rapid growth of medical evidence, which can be obtained from various sources, poses a challenge in collecting, appraising, and synthesizing the evidential information. Recent advancements in generative AI, exemplified by large language models, hold promise in facilitating the arduous task. However, developing accountable, fair, and inclusive models remains a complicated undertaking. In this perspective, we discuss the trustworthiness of generative AI in the context of automated summarization of medical evidence.

摘要

循证医学有望通过将最佳现有证据应用于医疗决策和实践来提高医疗质量。可以从各种来源获取的医疗证据呈快速增长趋势,这在收集、评估和综合证据信息方面带来了挑战。生成式人工智能的最新进展,例如大型语言模型,有望为这一艰巨任务提供便利。然而,开发负责任、公平和包容的模型仍然是一项复杂的任务。在此背景下,我们讨论了生成式人工智能在医疗证据自动摘要方面的可信度。

相似文献

1
Leveraging generative AI for clinical evidence synthesis needs to ensure trustworthiness.利用生成式人工智能进行临床证据综合需要确保其可信度。
J Biomed Inform. 2024 May;153:104640. doi: 10.1016/j.jbi.2024.104640. Epub 2024 Apr 10.
2
Trustworthy artificial intelligence and ethical design: public perceptions of trustworthiness of an AI-based decision-support tool in the context of intrapartum care.值得信赖的人工智能和道德设计:公众对基于人工智能的决策支持工具在产时护理背景下的可信度的看法。
BMC Med Ethics. 2023 Jun 20;24(1):42. doi: 10.1186/s12910-023-00917-w.
3
Recommendations for Clinicians, Technologists, and Healthcare Organizations on the Use of Generative Artificial Intelligence in Medicine: A Position Statement from the Society of General Internal Medicine.普通内科医学协会关于临床医生、技术专家和医疗保健组织在医学中使用生成式人工智能的建议:立场声明
J Gen Intern Med. 2025 Feb;40(3):694-702. doi: 10.1007/s11606-024-09102-0. Epub 2024 Nov 12.
4
Linking transcriptome and morphology in bone cells at cellular resolution with generative AI.利用生成式人工智能在细胞分辨率下将骨细胞中的转录组与形态学联系起来。
J Bone Miner Res. 2024 Dec 31;40(1):20-26. doi: 10.1093/jbmr/zjae151.
5
Attention is not all you need: the complicated case of ethically using large language models in healthcare and medicine.注意力并非全部所需:在医疗保健和医学中使用大型语言模型所涉及的复杂伦理问题。
EBioMedicine. 2023 Apr;90:104512. doi: 10.1016/j.ebiom.2023.104512. Epub 2023 Mar 15.
6
Leveraging Generative AI and Large Language Models: A Comprehensive Roadmap for Healthcare Integration.利用生成式人工智能和大语言模型:医疗保健整合综合路线图。
Healthcare (Basel). 2023 Oct 20;11(20):2776. doi: 10.3390/healthcare11202776.
7
Artificial intelligence for breast cancer detection and its health technology assessment: A scoping review.用于乳腺癌检测的人工智能及其健康技术评估:一项范围综述。
Comput Biol Med. 2025 Jan;184:109391. doi: 10.1016/j.compbiomed.2024.109391. Epub 2024 Nov 22.
8
Harnessing AI for enhanced evidence-based laboratory medicine (EBLM).利用人工智能加强循证检验医学(EBLM)。
Clin Chim Acta. 2025 Mar 1;569:120181. doi: 10.1016/j.cca.2025.120181. Epub 2025 Feb 3.
9
Ethical Application of Generative Artificial Intelligence in Medicine.生成式人工智能在医学中的伦理应用
Arthroscopy. 2025 Apr;41(4):874-885. doi: 10.1016/j.arthro.2024.12.011. Epub 2024 Dec 15.
10
Generative AI in healthcare: an implementation science informed translational path on application, integration and governance.生成式人工智能在医疗保健领域的应用、整合和治理:基于实施科学的转化途径。
Implement Sci. 2024 Mar 15;19(1):27. doi: 10.1186/s13012-024-01357-9.

引用本文的文献

1
Scalable Scientific Interest Profiling Using Large Language Models.使用大语言模型进行可扩展的科学兴趣剖析
ArXiv. 2025 Aug 19:arXiv:2508.15834v1.
2
Accelerating clinical evidence synthesis with large language models.利用大语言模型加速临床证据综合分析
NPJ Digit Med. 2025 Aug 8;8(1):509. doi: 10.1038/s41746-025-01840-7.
3
CLEAR: A vision to support clinical evidence lifecycle with continuous learning.清晰:通过持续学习支持临床证据生命周期的愿景。

本文引用的文献

1
GeneGPT: augmenting large language models with domain tools for improved access to biomedical information.GeneGPT:利用领域工具增强大型语言模型,以改善对生物医学信息的访问。
Bioinformatics. 2024 Feb 1;40(2). doi: 10.1093/bioinformatics/btae075.
2
Opportunities and challenges for ChatGPT and large language models in biomedicine and health.ChatGPT 和大型语言模型在生物医学和健康领域的机遇与挑战。
Brief Bioinform. 2023 Nov 22;25(1). doi: 10.1093/bib/bbad493.
3
Improving Fairness in AI Models on Electronic Health Records: The Case for Federated Learning Methods.
J Biomed Inform. 2025 Jul 29;169:104884. doi: 10.1016/j.jbi.2025.104884.
4
Leveraging long context in retrieval augmented language models for medical question answering.在检索增强语言模型中利用长上下文进行医学问答。
NPJ Digit Med. 2025 May 2;8(1):239. doi: 10.1038/s41746-025-01651-w.
5
Large Language Models and Their Applications in Drug Discovery and Development: A Primer.大语言模型及其在药物发现与开发中的应用:入门指南。
Clin Transl Sci. 2025 Apr;18(4):e70205. doi: 10.1111/cts.70205.
6
Evaluating a large language model's ability to answer clinicians' requests for evidence summaries.评估大型语言模型回答临床医生对证据总结请求的能力。
J Med Libr Assoc. 2025 Jan 14;113(1):65-77. doi: 10.5195/jmla.2025.1985.
7
From GPT to DeepSeek: Significant gaps remain in realizing AI in healthcare.从GPT到DeepSeek:在医疗保健领域实现人工智能仍存在重大差距。
J Biomed Inform. 2025 Mar;163:104791. doi: 10.1016/j.jbi.2025.104791. Epub 2025 Feb 10.
8
Semi-supervised learning from small annotated data and large unlabeled data for fine-grained Participants, Intervention, Comparison, and Outcomes entity recognition.从小规模标注数据和大规模未标注数据中进行半监督学习,用于细粒度的参与者、干预措施、对照和结果实体识别。
J Am Med Inform Assoc. 2025 Mar 1;32(3):555-565. doi: 10.1093/jamia/ocae326.
9
Demystifying Large Language Models for Medicine: A Primer.揭开医学领域大语言模型的神秘面纱:入门指南。
ArXiv. 2024 Nov 20:arXiv:2410.18856v3.
10
The doctor will polygraph you now.医生现在要给你做测谎检查。
Npj Health Syst. 2024;1(1):1. doi: 10.1038/s44401-024-00001-4. Epub 2024 Dec 5.
提高电子健康记录人工智能模型的公平性:联邦学习方法的案例
FAccT 23 (2023). 2023 Jun;2023:1599-1608. doi: 10.1145/3593013.3594102. Epub 2023 Jun 12.
4
Evaluating large language models on medical evidence summarization.基于医学证据总结对大语言模型进行评估。
NPJ Digit Med. 2023 Aug 24;6(1):158. doi: 10.1038/s41746-023-00896-7.
5
Publisher Correction: Large language models encode clinical knowledge.出版商更正:大语言模型编码临床知识。
Nature. 2023 Aug;620(7973):E19. doi: 10.1038/s41586-023-06455-0.
6
Automatically Summarizing Evidence from Clinical Trials: A Prototype Highlighting Current Challenges.自动总结临床试验证据:凸显当前挑战的一个原型
Proc Conf Assoc Comput Linguist Meet. 2023 May;2023:236-247.
7
Medicine is plagued by untrustworthy clinical trials. How many studies are faked or flawed?医学饱受不可信的临床试验之苦。有多少研究是伪造的或有缺陷的?
Nature. 2023 Jul;619(7970):454-458. doi: 10.1038/d41586-023-02299-w.
8
Large language models encode clinical knowledge.大语言模型编码临床知识。
Nature. 2023 Aug;620(7972):172-180. doi: 10.1038/s41586-023-06291-2. Epub 2023 Jul 12.
9
Achieving trust in health-behavior-change artificial intelligence apps (HBC-AIApp) development: A multi-perspective guide.实现健康行为改变人工智能应用程序(HBC-AIApp)开发中的信任:多视角指南。
J Biomed Inform. 2023 Jul;143:104414. doi: 10.1016/j.jbi.2023.104414. Epub 2023 Jun 3.
10
Retrieve, Summarize, and Verify: How Will ChatGPT Affect Information Seeking from the Medical Literature?检索、总结与验证:ChatGPT将如何影响从医学文献中获取信息?
J Am Soc Nephrol. 2023 Aug 1;34(8):1302-1304. doi: 10.1681/ASN.0000000000000166. Epub 2023 May 31.