Department of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, Messina 98100, Italy.
Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania "Luigi Vanvitelli", Naples 80100, Italy.
Mar Drugs. 2019 Jul 17;17(7):417. doi: 10.3390/md17070417.
This study aims to highlight the latest marine-derived technologies in the biomedical field. The dental field, in particular, uses many marine-derived biomaterials, including chitosan. Chitosan that is used in different fields of medicine, is analyzed in this review with the aim of highlighting its uses and advantages in the dental field. A literature search was conducted in scientific search engines, using keywords in order to achieve the highest possible number of results. A review of randomized controlled trials (RCT) was conducted to evaluate and process all the relevant results for chitosan and oral health. After a screening and a careful analysis of the literature, there were only 12 results highlighted. Chitosan performs different functions and it is used in different fields of dentistry in a safe and effective way. Among the uses of chitosan, we report on the remineralizing property of chitosan which hardens tissues of the tooth, and therefore its role as a desensibilizer used in toothpastes. According to our systematic review, the use of chitosan has shown better surgical healing of post-extraction oral wounds. Furthermore, some studies show a reduction in bacterial biofilm when used in dental cements. In addition, it has antibacterial, antifungal, hemostatic and other systemic properties which aid its use for drug delivering.
本研究旨在强调生物医学领域中最新的海洋衍生技术。在牙科领域，许多海洋衍生的生物材料被使用，包括壳聚糖。本综述分析了用于医学不同领域的壳聚糖，旨在突出其在牙科领域的用途和优势。在科学搜索引擎中进行了文献检索，使用了关键词，以获得尽可能多的结果。进行了随机对照试验（RCT）的综述，以评估和处理所有与壳聚糖和口腔健康相关的结果。经过筛选和仔细分析文献，仅突出了 12 个结果。壳聚糖具有不同的功能，以安全有效的方式应用于牙科的不同领域。壳聚糖的用途包括报告壳聚糖的再矿化特性，其使牙齿组织变硬，因此作为牙膏中的脱敏剂。根据我们的系统综述，壳聚糖的使用显示了拔牙后口腔伤口的更好的手术愈合。此外，一些研究表明，在牙科水泥中使用时，细菌生物膜减少。此外，壳聚糖具有抗菌、抗真菌、止血和其他全身特性，有助于其用于药物输送。
