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壳聚糖在牙釉质和牙本质再矿化中的作用:一项系统评价。

Role of Chitosan in Remineralization of Enamel and Dentin: A Systematic Review.

作者信息

Nimbeni Shruti B, Nimbeni Basavaraj S, Divakar Darshan Devang

机构信息

Department of Public Health, Texila American University, Guyana, South America.

Department of Clinical Research, Texila American University, Guyana, South America.

出版信息

Int J Clin Pediatr Dent. 2021 Jul-Aug;14(4):562-568. doi: 10.5005/jp-journals-10005-1971.

DOI:10.5005/jp-journals-10005-1971
PMID:34824515
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8585910/
Abstract

AIM AND OBJECTIVE

The purpose of this research was to analyze the role of chitosan in the remineralization of enamel and dentin.

MATERIALS AND METHODS

An electronic search was done for articles published from January 2009 to January 2020. A manual search was done from bibliographies of selected articles for relevant articles that were unexplored. Only studies conducted on the application of chitosan for remineralization of enamel and dentin were included in the study.

RESULTS

Of the 162 articles that were searched, only 15 studies were selected for the study. These studies met the inclusion criteria and were published from January 2009 to January 2020.

CONCLUSION

The review provides insight into the mechanism of remineralization of enamel and dentin. The properties of chitosan make it an ideal biomaterial that can be employed in the formulation of a novel remineralizing gel. However, more studies, clinical trials, and research are essential to transform chitosan-based remineralizing gels from research to clinical use.

CLINICAL SIGNIFICANCE

This review article opens a new window of opportunities for remineralizing enamel and dentin which have been long considered a challenging job.

HOW TO CITE THIS ARTICLE

Nimbeni SB, Nimbeni BS, Divakar DD. Role of Chitosan in Remineralization of Enamel and Dentin: A Systematic Review. Int J Clin Pediatr Dent 2021;14(4):562-568.

摘要

目的与目标

本研究旨在分析壳聚糖在牙釉质和牙本质再矿化中的作用。

材料与方法

对2009年1月至2020年1月发表的文章进行电子检索。从所选文章的参考文献中进行人工检索,以查找未被探索的相关文章。本研究仅纳入了关于壳聚糖用于牙釉质和牙本质再矿化的研究。

结果

在检索到的162篇文章中,仅15项研究被选入本研究。这些研究符合纳入标准,且发表于2009年1月至2020年1月。

结论

该综述深入探讨了牙釉质和牙本质再矿化的机制。壳聚糖的特性使其成为一种理想的生物材料,可用于新型再矿化凝胶的配方。然而,需要更多的研究、临床试验和调查,才能将基于壳聚糖的再矿化凝胶从研究转化为临床应用。

临床意义

这篇综述文章为牙釉质和牙本质再矿化打开了一扇新的机会之窗,而牙釉质和牙本质再矿化长期以来一直被认为是一项具有挑战性的工作。

如何引用本文

Nimbeni SB, Nimbeni BS, Divakar DD.壳聚糖在牙釉质和牙本质再矿化中的作用:一项系统综述。《国际临床儿科学牙科杂志》2021;14(4):562 - 568。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8bf/8585910/5fc415c64582/ijcpd-14-562-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8bf/8585910/0f03278eef75/ijcpd-14-562-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8bf/8585910/5fc415c64582/ijcpd-14-562-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8bf/8585910/0f03278eef75/ijcpd-14-562-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8bf/8585910/5fc415c64582/ijcpd-14-562-g002.jpg

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J Dent. 2019 May;84:67-75. doi: 10.1016/j.jdent.2019.03.006. Epub 2019 Apr 2.
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In-vitro subsurface remineralisation of artificial enamel white spot lesions pre-treated with chitosan.壳聚糖预处理人工釉质白斑表面下再矿化的体外研究。
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Bioengineering (Basel). 2025 Feb 28;12(3):248. doi: 10.3390/bioengineering12030248.
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Biomimetics (Basel). 2025 Feb 18;10(2):120. doi: 10.3390/biomimetics10020120.
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