Schleicher S M, Milstein H J
Cutis. 1985 Aug;36(2):147-8.
Disseminated granuloma annulare is often a chronic disorder that may prove refractory to treatment and lead to prolonged cosmetic disfigurement. In a patient with disseminated granuloma annulare that was unresponsive to multiple therapeutic regimens, administration of isotretinoin resulted in rapid clearing of nearly all lesions. To our knowledge this is the first reported case in which this agent was used to treat disseminated granuloma annulare.
播散性环状肉芽肿通常是一种慢性疾病，可能对治疗有抵抗性，并导致长期的外观毁损。在一名对多种治疗方案均无反应的播散性环状肉芽肿患者中，给予异维A酸后几乎所有皮损迅速消退。据我们所知，这是首次报道使用该药物治疗播散性环状肉芽肿的病例。
