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40岁以下人群的憩室炎

Diverticulitis in the Under-40 Population.

作者信息

Jacqueline Danisi, Lince Kimberly, DeMario Virgil K, Zarutskie Alexander, Cisse Shannon, Sogunro Olutayo

机构信息

Medicine, University of the Incarnate Word School of Osteopathic Medicine, San Antonio, USA.

Biomolecular Science, Central Connecticut State University, New Britain, USA.

出版信息

Cureus. 2024 Mar 14;16(3):e56190. doi: 10.7759/cureus.56190. eCollection 2024 Mar.

Abstract

BACKGROUND

As obesity and lifestyle factors become more prevalent in younger populations, we are diagnosing and treating diverticulitis in younger patients. In this study, the demographics, risk factors for the development, and treatment of acute diverticulitis were assessed focusing on patients under the age of 40.

METHODS

A retrospective review of the electronic medical records of a cohort of subjects diagnosed with diverticulitis was performed. Inclusion criteria included patients aged 18-40 who were treated for acute diverticulitis with or without any complications.

RESULTS

Of the 109 patients, 40 patients required surgery, and 69 patients were managed conservatively. Analysis showed that the Hinchey classification (p<0.001) was the strongest predictor of treatment modality.

CONCLUSIONS

As the incidence of diverticulitis has increased in recent decades, so too has the frequency with which elective surgical procedures are performed as treatment. While these procedures are vital components in the management of diverticulitis, the majority of research comparing conservative versus surgical treatments has been done in patients over 50 years old. Although diverticulitis has been classically thought of as a disease of the elderly, it has become more prevalent in younger populations due to the rise of obesity and lifestyle modification in the under-40 population. Although the prevalence of treatment and diagnosis of acute diverticulitis in younger patients has risen, there is a paucity of data surrounding treatment protocols for diverticulitis in association with patient symptoms for patients under the age of 40 years old. Our study has found that there is a higher incidence of complications in diverticulitis in patients under the age of 40. Additionally, when considering the pattern of complication presentation in younger patients with complicated diverticulitis, surgical intervention might not be appropriate. The current treatment algorithm relates diverticulitis complications with surgical interventions. However, our data suggest that patients under the age of 40 presenting with abscesses or strictures may not need surgical intervention. This information could be particularly helpful in guiding physicians and younger patients in selecting the best choice of care and minimizing complications. Additionally, further research should help guide treatment protocol in this specific population of patients, as there is a lack of established guidelines pertaining to diverticulitis surrounding younger patients.

摘要

背景

随着肥胖和生活方式因素在年轻人群中越来越普遍,我们正在对年轻患者进行憩室炎的诊断和治疗。在本研究中,以40岁以下患者为重点,评估了急性憩室炎的人口统计学、发病风险因素及治疗情况。

方法

对一组被诊断为憩室炎的受试者的电子病历进行回顾性分析。纳入标准包括年龄在18至40岁之间、接受过急性憩室炎治疗(无论有无并发症)的患者。

结果

109例患者中,40例需要手术治疗,69例接受保守治疗。分析表明,欣奇分类(p<0.001)是治疗方式的最强预测因素。

结论

近几十年来,憩室炎的发病率有所上升,作为治疗手段的择期手术的频率也随之增加。虽然这些手术是憩室炎治疗的重要组成部分,但大多数比较保守治疗与手术治疗的研究都是在50岁以上的患者中进行的。尽管憩室炎传统上被认为是一种老年疾病,但由于40岁以下人群肥胖率上升和生活方式改变,它在年轻人群中变得更加普遍。虽然年轻患者急性憩室炎的诊断和治疗患病率有所上升,但关于40岁以下患者憩室炎与患者症状相关的治疗方案的数据却很少。我们的研究发现,40岁以下憩室炎患者的并发症发生率较高。此外,考虑到年轻复杂憩室炎患者的并发症表现模式,手术干预可能并不合适。目前的治疗算法将憩室炎并发症与手术干预联系起来。然而,我们的数据表明,出现脓肿或狭窄的40岁以下患者可能不需要手术干预。这些信息对于指导医生和年轻患者选择最佳治疗方案并减少并发症可能特别有帮助。此外,由于缺乏针对年轻患者憩室炎的既定指南,进一步的研究应有助于指导这一特定患者群体的治疗方案。

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