From the Departments of Nuclear Medicine.
Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Clin Nucl Med. 2024 Sep 1;49(9):e457-e458. doi: 10.1097/RLU.0000000000005172. Epub 2024 Apr 12.
We report 18 F-FDG PET/CT appearances of intracholecystic papillary neoplasm (ICPN) in the gallbladder neck and duct of a 74-year-old woman with a history of hepatitis B cirrhosis. The lesion presented with a large and sessile soft mass in the neck and duct of gallbladder with obvious glucose metabolism on PET/CT images, which was confirmed pathologically as ICPN (gastric foveolar type) with high-grade intraepithelial neoplasia. ICPN localized in the gallbladder neck and duct is extremely rare, and is easily misdiagnosed as gallbladder carcinoma. Our report aids in the application of PET/CT in the differential diagnosis of ICPN and guiding early surgery.
我们报告了一例 74 岁女性的病例，该患者有乙型肝炎肝硬化病史，其胆囊颈部和胆管内出现了 18 F-FDG PET/CT 表现的胆囊内乳头状肿瘤（ICPN）。病变在胆囊颈部和胆管呈现出一个大的、无蒂的软组织肿块，在 PET/CT 图像上显示明显的葡萄糖代谢，经病理证实为 ICPN（胃小凹型）伴高级别上皮内瘤变。胆囊颈部和胆管内的 ICPN 极为罕见，容易误诊为胆囊癌。我们的报告有助于在鉴别诊断 ICPN 和指导早期手术方面应用 PET/CT。
