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单剂量布洛芬诱发史蒂文斯-约翰逊综合征。

Single-dose ibuprofen induced Stevens-Johnson Syndrome.

作者信息

Alhatemi Ahmed Qasim Mohammed, Hashim Hashim Talib, Al-Tarbosh Muhamad Abdulrahman Shyea, Abdulhussain Rand, Hashim Ali Talib

机构信息

Department of Internal Medicine Al Nasiriyah Teaching Hospital Thi Qar Iraq.

College of Medicine Warith Al Anbiyaa University Karbala Iraq.

出版信息

Clin Case Rep. 2024 Apr 15;12(4):e8574. doi: 10.1002/ccr3.8574. eCollection 2024 Apr.

Abstract

KEY CLINICAL MESSAGE

Ibuprofen single dose may rarely induce Stevens-Johnson Syndrome, emphasizing the vital need for heightened vigilance in healthcare and public awareness for safer medication practices.

ABSTRACT

Stevens-Johnson Syndrome (SJS) is a severe and potentially life-threatening skin disorder associated with certain medications, including ibuprofen. We present a case of a 45-year-old woman who developed SJS following a single dose of ibuprofen. Despite its rarity, this case underscores the importance of heightened vigilance in healthcare and public awareness regarding the potential risks of commonly used medications. Prompt recognition of SJS symptoms and immediate medical intervention are crucial for patient outcomes. Healthcare providers should exercise caution when prescribing ibuprofen, particularly in patients with a history of adverse drug reactions. This case emphasizes the need for ongoing monitoring, patient education, and informed decision-making to promote medication safety and optimal patient care.

摘要

关键临床信息

单剂量布洛芬极少会引发史蒂文斯-约翰逊综合征,这凸显了医疗保健领域提高警惕以及提高公众对更安全用药做法的认识的迫切需求。

摘要

史蒂文斯-约翰逊综合征(SJS)是一种严重且可能危及生命的皮肤疾病,与某些药物有关,包括布洛芬。我们报告一例45岁女性在服用单剂量布洛芬后发生SJS的病例。尽管这种情况罕见,但该病例强调了医疗保健领域提高警惕以及提高公众对常用药物潜在风险认识的重要性。及时识别SJS症状并立即进行医疗干预对患者预后至关重要。医疗保健提供者在开具布洛芬处方时应谨慎,尤其是对有药物不良反应史的患者。该病例强调需要持续监测、患者教育以及明智决策,以促进用药安全和优化患者护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ac1/11017452/ae1f1d814566/CCR3-12-e8574-g002.jpg

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