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评估80岁及以上居家中国老年人的认知障碍:对13000名参与者进行的详细调查,重点关注人口统计学因素、社会参与度和疾病患病率。

Assessing cognitive impairment in home-dwelling Chinese elders aged 80+: a detailed survey of 13,000 participants focusing on demographic factors, social engagement, and disease prevalence.

作者信息

Bian Sensen, Tian Xiaobing, Meng Fanli, Xu Chunjie, Zhao Yan, Gao Qian, Bian Chengzhi

机构信息

Department of Public Health, Hangzhou Normal University, Hangzhou, Zhejiang, China.

Nanjing Zhiyuan Healthcare Training Center, Jiangsu SuYi Health Care Research Institute, Nanjing, Jiangsu, China.

出版信息

Front Psychiatry. 2024 Apr 2;15:1355708. doi: 10.3389/fpsyt.2024.1355708. eCollection 2024.

DOI:10.3389/fpsyt.2024.1355708
PMID:38628263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11019016/
Abstract

INTRODUCTION

Cognitive Impairment (CI) in the elderly, encompassing conditions ranging from Mild Cognitive Impairment (MCI) to dementia, represents a growing public health concern globally. This study aims to investigate the prevalence and correlates of CI among individuals aged 80 and above.

METHODS

The study conducts 13,027 elderly individual's door-to-door surveys, followed by the cross-tabulation of analysis data, logistic regression analysis, and health condition assessments to examine various determinants of CI.

RESULTS

The current study's key findings demonstrate sub-statical correlations between CI and various factors, including educational attainment, marital status, and gender. Pronounced differences are evident between urban and rural demographics. Furthermore, aspects of social engagement, notably communication proficiency and sensory capabilities, exhibit a strong association with CI. Logistic regression analysis highlights that residing in rural areas (Odds Ratio [OR] = 0.637) and being female (OR = 0.71) are linked to a decreased risk of CI. In contrast, behavioral and health-related variables present a complex picture. Specifically, aggressive behavior (Adjusted OR = 1.881) and symptoms of depression (Adjusted OR = 0.549) contrast with conditions such as asthma (OR= 2.857) and cerebral infarction (OR=1.348), which elevate the risk of CI. Intriguingly, hyperlipidemia (OR= 0.671) appears to confer a protective effect against CI.

CONCLUSION

The study highlights the complexity of factors affecting CI in the elderly, advocating for a comprehensive approach to understanding and managing cognitive health.

摘要

引言

老年人的认知障碍(CI),涵盖从轻度认知障碍(MCI)到痴呆症等一系列情况,是全球日益受到关注的公共卫生问题。本研究旨在调查80岁及以上人群中CI的患病率及其相关因素。

方法

该研究对13027名老年人进行了挨家挨户的调查,随后对分析数据进行交叉制表、逻辑回归分析和健康状况评估,以检查CI的各种决定因素。

结果

当前研究的主要发现表明,CI与各种因素之间存在亚静态相关性,包括教育程度、婚姻状况和性别。城乡人口统计数据之间存在明显差异。此外,社会参与方面,特别是沟通能力和感官能力,与CI表现出强烈关联。逻辑回归分析强调,居住在农村地区(优势比[OR]=0.637)和女性(OR=0.71)与CI风险降低有关。相比之下,行为和健康相关变量呈现出复杂的情况。具体而言,攻击性行为(调整后的OR=1.881)和抑郁症状(调整后的OR=0.549)与哮喘(OR=2.857)和脑梗死(OR=1.348)等疾病形成对比,这些疾病会增加CI的风险。有趣的是,高脂血症(OR=0.671)似乎对CI具有保护作用。

结论

该研究强调了影响老年人CI的因素的复杂性,主张采用综合方法来理解和管理认知健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ba0/11019016/fa618fc8fad8/fpsyt-15-1355708-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ba0/11019016/fa618fc8fad8/fpsyt-15-1355708-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ba0/11019016/fa618fc8fad8/fpsyt-15-1355708-g001.jpg

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