Sinha Pranam, Boopathi Priya, Suresh Vasugi, Pitchiah Sivaperumal
Physiology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Prosthodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Cureus. 2024 Mar 18;16(3):e56355. doi: 10.7759/cureus.56355. eCollection 2024 Mar.
Background Currently, nanotechnology is a rapidly advancing field of research. Because of their nanoscale dimensions, nanoparticles (NPs) find application in a wide range of industries, including engineering and medicine. The leaves of have anti-inflammatory qualities. The purpose of this study was to create SrO NPs isolated from the leaves of aqueous extract and to evaluate their anti-inflammatory efficacy. The . saltmarsh, commonly known as South-Indian Seepweed, is a mangrove-associated plant and has been used as traditional medicine for decades with multifunctional biological activity. Objectives The aim of our study is to biosynthesize strontium oxide NPs from saltmarsh and to see whether they have any anti-inflammatory properties. Materials and methods In the present study, the pharmacological significance was studied using crude extract and synthesized SrO NPs from The synthesized SrO NPs were characterized using UV spectrophotometry. The anti-inflammatory assay was analyzed using egg albumin denaturation. SrO NPs' peak observance was found at 630 nm, and a graph was plotted for the zone of inhibition vs concentration and compared with the standard. Results It was observed that the color of the SrO NPs deepened during the synthesis process. Furthermore, at a wavelength of 630 nm, the UV spectrum analysis showed a noteworthy absorption value of 1.4. The activity of inflammatory enzymes is significantly impacted by the anti-inflammatory properties of SrO NPs in the protein denaturation inhibition test. Conclusions The application of SrO NPs in the synthesis process has the potential to enhance the anti-inflammatory activity of as evidenced by the observed increase in anti-inflammatory capacity and defense against infections and injury.
背景 目前,纳米技术是一个快速发展的研究领域。由于其纳米级尺寸,纳米颗粒(NPs)在包括工程和医学在内的广泛行业中得到应用。[植物名称]的叶子具有抗炎特性。本研究的目的是从[植物名称]水提取物中制备分离出的氧化锶纳米颗粒,并评估其抗炎效果。[植物名称],通常被称为南印度海蓬子,是一种与红树林相关的植物,几十年来一直被用作具有多功能生物活性的传统药物。
目的 我们研究的目的是从[植物名称]盐沼中生物合成氧化锶纳米颗粒,并观察它们是否具有任何抗炎特性。
材料和方法 在本研究中,使用粗提取物和从[植物名称]合成的氧化锶纳米颗粒研究其药理意义。使用紫外分光光度法对合成的氧化锶纳米颗粒进行表征。使用蛋清蛋白变性分析抗炎试验。发现氧化锶纳米颗粒的峰值在630nm处,绘制了抑制区与浓度的关系图并与标准进行比较。
结果 观察到在合成过程中氧化锶纳米颗粒的颜色加深。此外,在630nm波长处,紫外光谱分析显示出1.4的显著吸收值。在蛋白质变性抑制试验中,氧化锶纳米颗粒的抗炎特性对炎症酶的活性有显著影响。
结论 氧化锶纳米颗粒在合成过程中的应用有可能增强[植物名称]的抗炎活性,观察到的抗炎能力增加以及对感染和损伤的防御证明了这一点。