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结构评估网络服务器:适用于蛋白质、复合物等。

The structure assessment web server: for proteins, complexes and more.

机构信息

Biozentrum, University of Basel, Switzerland.

SIB Swiss Institute of Bioinformatics, Computational Structural Biology, Basel, Switzerland.

出版信息

Nucleic Acids Res. 2024 Jul 5;52(W1):W318-W323. doi: 10.1093/nar/gkae270.

Abstract

The 'structure assessment' web server is a one-stop shop for interactive evaluation and benchmarking of structural models of macromolecular complexes including proteins and nucleic acids. A user-friendly web dashboard links sequence with structure information and results from a variety of state-of-the-art tools, which facilitates the visual exploration and evaluation of structure models. The dashboard integrates stereochemistry information, secondary structure information, global and local model quality assessment of the tertiary structure of comparative protein models, as well as prediction of membrane location. In addition, a benchmarking mode is available where a model can be compared to a reference structure, providing easy access to scores that have been used in recent CASP experiments and CAMEO. The structure assessment web server is available at https://swissmodel.expasy.org/assess.

摘要

“结构评估”网络服务器是一个一站式服务,用于对包括蛋白质和核酸在内的大分子复合物的结构模型进行交互式评估和基准测试。一个用户友好的网络仪表板将序列与结构信息以及来自各种最先进工具的结果联系起来,方便对结构模型进行可视化探索和评估。该仪表板集成了立体化学信息、二级结构信息、比较蛋白质模型的三级结构的整体和局部模型质量评估,以及膜位置预测。此外,还提供了基准测试模式,其中可以将模型与参考结构进行比较,方便访问最近 CASP 实验和 CAMEO 中使用的分数。结构评估网络服务器可在 https://swissmodel.expasy.org/assess 上获得。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03ca/11223858/d82fa1cf689b/gkae270figgra1.jpg

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