Sainsbury C P, Newcombe R G, Hughes I A
Arch Dis Child. 1985 Sep;60(9):832-6. doi: 10.1136/adc.60.9.832.
A retrospective analysis of the medical records of 86 children in prolonged remission from acute lymphoblastic leukaemia was performed to calculate changes in the rate of increase in height and weight gain. The rate of increase in height decreased during initial treatment, and the potential for final adult height was not regained. Weight gain was excessive; this started during treatment and persisted into the remission years. Values of weight adjusted for height did not return to values found before treatment until eight years after diagnosis. Several factors can account for this weight gain, but there is a practical need to provide dietary advice, particularly when chemotherapy is stopped.
对86名急性淋巴细胞白血病长期缓解期儿童的病历进行回顾性分析,以计算身高增长速率和体重增加的变化。在初始治疗期间身高增长速率下降,最终成人身高的潜力未能恢复。体重增加过多;这在治疗期间开始并持续到缓解期。根据身高调整后的体重值直到诊断后八年才恢复到治疗前的水平。有几个因素可以解释这种体重增加,但实际需要提供饮食建议,尤其是在化疗停止时。