School of Nursing, The Hong Kong Polytechnic University, Hong Kong, China.
Department of Mood Disorders, Soochow University Affiliated Guangji Hospital, Jiang Su, China.
PLoS One. 2024 Apr 18;19(4):e0302235. doi: 10.1371/journal.pone.0302235. eCollection 2024.
Physical exercise (PE) is essential for alleviating the symptoms of sarcopenia. Low motivation is a major barrier to PE. Mindfulness-based intervention (MBI) has the potential to improve motivation. However, few studies have used a mindfulness-based PE (MBPE) intervention among older people with sarcopenia.
To assess the feasibility, acceptability and preliminary effects of the MBPE program among community-dwelling older people with sarcopenia.
A two-arm pilot randomised controlled trial will be conducted to assess the feasibility, acceptability and preliminary effects of an MBPE program among community-dwelling older people with sarcopenia. A total of 60 participants will be randomised into the intervention group, receiving the MBPE intervention twice a week over 12 weeks, or the control group, receiving health education with the same duration, number of sessions and frequency as the intervention group. Each session of the MBPE program will last about 60 min, including 5-10- min introduction, 20-min MBI, 30-min PE and 5-10-min sharing and discussion. The primary outcomes will be the feasibility (i.e., the time spent recruiting participants, the eligibility rate and the recruitment rate) and acceptability (i.e., the attendance rate, completion rate and attrition rate) of the MBPE program. The secondary outcomes will be the preliminary effects of the MBPE program on symptoms of sarcopenia, motivation for PE, psychological well-being, mindfulness level, physical activity level and quality of life. Individual interviews will be conducted to identify the strengths, limitations and therapeutic components of the intervention. The quantitative data will be analysed by generalised estimating equations. The qualitative data will be analysed by Braun and Clarke's thematic approach.
The findings of this study will be able to provide evidence for the health professionals in adopting MBPE as a supportive intervention for the older adults with sarcopenia and the groundworks for the researchers in developing non-pharmacological intervention for older adults. The positive effects could facilitate healthy ageing and relief the burden of the medical system, especially in the countries facing the ageing population.
NCT05982067; ClinicalTrials.gov.
体育锻炼（PE）对于缓解肌少症症状至关重要。低动机是进行体育锻炼的主要障碍。基于正念的干预（MBI）有可能提高动机。然而，很少有研究在患有肌少症的老年人中使用基于正念的体育锻炼（MBPE）干预。
评估基于正念的体育锻炼计划在社区居住的肌少症老年人中的可行性、可接受性和初步效果。
将进行一项两臂随机对照试验，以评估基于正念的体育锻炼计划在社区居住的肌少症老年人中的可行性、可接受性和初步效果。共有 60 名参与者将被随机分为干预组，每周接受两次基于正念的体育锻炼干预，共 12 周，或对照组，接受健康教育，持续时间、次数和频率与干预组相同。MBPE 方案的每个方案大约持续 60 分钟，包括 5-10 分钟的介绍，20 分钟的 MBI，30 分钟的体育锻炼和 5-10 分钟的分享和讨论。主要结果将是 MBPE 方案的可行性（即招募参与者所花费的时间、合格率和招募率）和可接受性（即出勤率、完成率和失访率）。次要结果将是 MBPE 方案对肌少症症状、体育锻炼动机、心理健康、正念水平、身体活动水平和生活质量的初步效果。将进行个体访谈，以确定干预措施的优势、局限性和治疗成分。定量数据将通过广义估计方程进行分析。定性数据将通过 Braun 和 Clarke 的主题方法进行分析。
这项研究的结果将能够为健康专业人员提供将 MBPE 作为支持患有肌少症的老年人的干预措施的证据，并为研究人员为老年人开发非药物干预措施奠定基础。积极的影响可以促进健康老龄化并减轻医疗系统的负担，特别是在面临人口老龄化的国家。
NCT05982067；ClinicalTrials.gov。
