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基于超广角扫描激光检眼镜的糖尿病视网膜病变病灶自动识别算法

Algorithm of automatic identification of diabetic retinopathy foci based on ultra-widefield scanning laser ophthalmoscopy.

作者信息

Wang Jie, Wang Su-Zhen, Qin Xiao-Lin, Chen Meng, Zhang Heng-Ming, Liu Xin, Xiang Meng-Jun, Hu Jian-Bin, Huang Hai-Yu, Lan Chang-Jun

机构信息

Aier Eye Hospital (East of Chengdu), Chengdu 610051, Sichuan Province, China.

Department of Ophthalmology, Chengdu First People's Hospital, Chengdu 610095, Sichuan Province, China.

出版信息

Int J Ophthalmol. 2024 Apr 18;17(4):610-615. doi: 10.18240/ijo.2024.04.02. eCollection 2024.

Abstract

AIM

To propose an algorithm for automatic detection of diabetic retinopathy (DR) lesions based on ultra-widefield scanning laser ophthalmoscopy (SLO).

METHODS

The algorithm utilized the FasterRCNN (Faster Regions with CNN features)+ResNet50 (Residua Network 50)+FPN (Feature Pyramid Networks) method for detecting hemorrhagic spots, cotton wool spots, exudates, and microaneurysms in DR ultra-widefield SLO. Subimage segmentation combined with a deeper residual network FasterRCNN+ResNet50 was employed for feature extraction to enhance intelligent learning rate. Feature fusion was carried out by the feature pyramid network FPN, which significantly improved lesion detection rates in SLO fundus images.

RESULTS

By analyzing 1076 ultra-widefield SLO images provided by our hospital, with a resolution of 2600×2048 dpi, the accuracy rates for hemorrhagic spots, cotton wool spots, exudates, and microaneurysms were found to be 87.23%, 83.57%, 86.75%, and 54.94%, respectively.

CONCLUSION

The proposed algorithm demonstrates intelligent detection of DR lesions in ultra-widefield SLO, providing significant advantages over traditional fundus color imaging intelligent diagnosis algorithms.

摘要

目的

提出一种基于超广角扫描激光检眼镜(SLO)的糖尿病视网膜病变(DR)病变自动检测算法。

方法

该算法利用FasterRCNN(带CNN特征的快速区域)+ResNet50(残差网络50)+FPN(特征金字塔网络)方法检测DR超广角SLO中的出血斑、棉絮斑、渗出物和微动脉瘤。采用子图像分割结合更深的残差网络FasterRCNN+ResNet50进行特征提取,以提高智能学习率。通过特征金字塔网络FPN进行特征融合,显著提高了SLO眼底图像中病变的检测率。

结果

通过分析我院提供的1076张分辨率为2600×2048 dpi的超广角SLO图像,发现出血斑、棉絮斑、渗出物和微动脉瘤的准确率分别为87.23%、83.57%、86.75%和54.94%。

结论

所提出的算法展示了在超广角SLO中对DR病变的智能检测,与传统眼底彩色成像智能诊断算法相比具有显著优势。

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