Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing 211166, China; Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing 211166, China; Changzhou Medical Center, Nanjing Medical University, Changzhou 213003, China; The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou Second People's Hospital, Changzhou 213000, China.
STAR Protoc. 2024 Jun 21;5(2):103023. doi: 10.1016/j.xpro.2024.103023. Epub 2024 Apr 18.
Social cooperation is fundamentally important for group animals but rarely studied in mice because of their natural aggressiveness. Here, we present a new water-reward assay to investigate mutualistic cooperative behavior in mice. We describe the construction of the apparatus and provide details of the procedures and analysis for investigators to characterize and quantify the mutualistic cooperative behavior. This protocol has been validated in mice and can be used for investigating mechanisms of cooperation. For complete details on the use and execution of this protocol, please refer to Zhang et al. and Wang et al..
社会合作对群居动物至关重要，但由于老鼠具有天然的攻击性，因此很少对其进行研究。在这里，我们介绍了一种新的水奖励测定法，用于研究老鼠的互利合作行为。我们描述了仪器的构建，并提供了程序的详细信息和分析，供研究人员对互利合作行为进行特征描述和量化。该方案已在小鼠中得到验证，可用于研究合作的机制。如需详细了解本方案的使用和执行情况，请参考 Zhang 等人和 Wang 等人的研究。
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