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[伴有颅内肿瘤形成的急性髓系白血病——病例报告]

[Acute myeloid leukemia with intracranial tumor formation--case report].

作者信息

Moto A, Nakada J, Oka N, Endo S, Takaku A, Kitagawa M

出版信息

No Shinkei Geka. 1985 Aug;13(8):889-93.

PMID:3864029
Abstract

A 44-year-old house-wife was admitted to the hematological clinic of our hospital on December 21, 1981 for the treatment of acute myeloid leukemia. Hematological examination showed severe anemia, leukocytosis and thrombocytopenia. She was soon started on DCMP therapy (Daunomycin, Cytosine arabinoside, 6-MP and prednisolone). After several repeats of remission and aggravation, she suffered from vertigo, nausea and vomiting in early August of 1982. The CT scan and angiography showed a mass lesion in the middle of the posterior cranial fossa. On August 26, surgical extirpation of the tumor locating in the vermis of the cerebellum was performed successfully. On gross examination the tumor revealed smooth yellowish-red surface, elastic in consistency and measured 40 X 40 X 30 mm in size. Histologically it comprised the leukemic cells. The pathology of the central nervous system due to leukemic cells was discussed in relation to the pertinent literature, including the CT findings and the indication of the surgical treatment.

摘要

一名44岁的家庭主妇于1981年12月21日入住我院血液科,接受急性髓细胞白血病的治疗。血液学检查显示严重贫血、白细胞增多和血小板减少。她很快开始接受DCMP疗法(柔红霉素、阿糖胞苷、6-巯基嘌呤和泼尼松龙)。经过几次缓解和加重后,她于1982年8月初出现眩晕、恶心和呕吐。CT扫描和血管造影显示后颅窝中部有一个肿块病变。8月26日,成功地对位于小脑蚓部的肿瘤进行了手术切除。大体检查显示肿瘤表面光滑,呈黄红色,质地有弹性,大小为40×40×30mm。组织学上它由白血病细胞组成。结合相关文献,包括CT表现和手术治疗指征,对白血病细胞引起的中枢神经系统病理进行了讨论。

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