Orstavik D
Acta Odontol Scand. 1985 Aug;43(4):231-9. doi: 10.3109/00016358509046503.
Nine commercial dental amalgams were tested for antibacterial properties in vitro. A bactericidal test on salivary bacteria, a growth inhibition test on Streptococcus mutans OMZ 176, and a time-dependent bactericidal test on Strep. mutans were used. All amalgams displayed some antibacterial properties. Dispersalloy and Revalloy were strongly antibacterial in all tests; ANA 2000 and Sybraloy killed Strep. mutans but were less potent in the salivary test and in the growth inhibition experiments. The copper amalgams, Neo-Silbrin and Cupromuc, were the most active in the salivary test but less inhibitory in the growth curve experiments. Spheraloy, Indiloy, and Amalcap showed intermediate activity in the salivary bactericidal test but were relatively weak in the growth inhibition studies. Analysis of Hg, Ag, and Cu in media from the growth inhibition studies showed release of Hg from the copper amalgams and, particularly, from Revalloy; Indiloy gave off Ag, whereas Neo-Silbrin, Cupromuc, Sybraloy, and ANA 2000 released more Cu than the other brands.
对九种市售牙科汞合金进行了体外抗菌性能测试。采用了对唾液细菌的杀菌试验、对变形链球菌OMZ 176的生长抑制试验以及对变形链球菌的时间依赖性杀菌试验。所有汞合金均表现出一定的抗菌性能。Dispersalloy和Revalloy在所有试验中均具有较强的抗菌性;ANA 2000和Sybraloy可杀死变形链球菌,但在唾液试验和生长抑制实验中的效力较低。铜汞合金Neo-Silbrin和Cupromuc在唾液试验中活性最高,但在生长曲线实验中的抑制作用较小。Spheraloy、Indiloy和Amalcap在唾液杀菌试验中表现出中等活性,但在生长抑制研究中相对较弱。对生长抑制研究培养基中的汞、银和铜进行分析表明,铜汞合金尤其是Revalloy会释放汞;Indiloy释放银,而Neo-Silbrin、Cupromuc、Sybraloy和ANA 2000释放的铜比其他品牌更多。