Pope H G, Hudson J I, Jonas J M, Yurgelun-Todd D
J Clin Psychopharmacol. 1985 Dec;5(6):320-7.
Follow-ups for periods of up to 2 years on 20 bulimic subjects treated with antidepressants are reported. At the time last seen in follow-up, 19 (95%) of the subjects had experienced at least a partial improvement in their bulimia, and 10 (50%) had experienced a complete remission of bulimic symptoms. In addition, most subjects displayed a marked reduction in depressive symptoms. This suggests that antidepressants do not merely reduce binge eating per se, but produce a more general therapeutic effect for bulimic patients. However, these promising findings must be tempered by the fact that antidepressant treatment is not always simple and may require extensive management over the long term.
报告了对20名接受抗抑郁药治疗的贪食症患者长达2年的随访情况。在随访中最后一次见到这些患者时，19名（95%）患者的贪食症至少有部分改善，10名（50%）患者的贪食症症状完全缓解。此外，大多数患者的抑郁症状明显减轻。这表明抗抑郁药不仅仅是减少暴饮暴食本身，而是对贪食症患者产生更广泛的治疗效果。然而，这些有前景的发现必须考虑到抗抑郁药治疗并不总是简单的，可能需要长期的广泛管理这一事实。
