Thanjavur Naveen, Bugude Laxmi, Kim Young-Joon
Department of Electronic Engineering, Gachon University, Seongnam 13120, Republic of Korea.
Department of Semiconductor Engineering, Gachon University, Seongnam 13120, Republic of Korea.
Biosensors (Basel). 2025 Jan 10;15(1):38. doi: 10.3390/bios15010038.
Integrating functional materials with photonic and optoelectronic technologies has revolutionized medical diagnostics, enhancing imaging and sensing capabilities. This review provides a comprehensive overview of recent innovations in functional materials, such as quantum dots, perovskites, plasmonic nanomaterials, and organic semiconductors, which have been instrumental in the development of diagnostic devices characterized by high sensitivity, specificity, and resolution. Their unique optical properties enable real-time monitoring of biological processes, advancing early disease detection and personalized treatment. However, challenges such as material stability, reproducibility, scalability, and environmental sustainability remain critical barriers to their clinical translation. Breakthroughs such as green synthesis, continuous flow production, and advanced surface engineering are addressing these limitations, paving the way for next-generation diagnostic tools. This article highlights the transformative potential of interdisciplinary research in overcoming these challenges and emphasizes the importance of sustainable and scalable strategies for harnessing functional materials in medical diagnostics. The ultimate goal is to inspire further innovation in the field, enabling the creation of practical, cost-effective, and environmentally friendly diagnostic solutions.
将功能材料与光子和光电子技术相结合，彻底改变了医学诊断，增强了成像和传感能力。本综述全面概述了功能材料的最新创新，如量子点、钙钛矿、等离子体纳米材料和有机半导体，这些材料在开发具有高灵敏度、特异性和分辨率的诊断设备中发挥了重要作用。它们独特的光学特性能够对生物过程进行实时监测，推动早期疾病检测和个性化治疗。然而，材料稳定性、可重复性、可扩展性和环境可持续性等挑战仍然是其临床转化的关键障碍。绿色合成、连续流生产和先进表面工程等突破正在解决这些限制，为下一代诊断工具铺平道路。本文强调了跨学科研究在克服这些挑战方面的变革潜力，并强调了可持续和可扩展策略在医学诊断中利用功能材料的重要性。最终目标是激发该领域的进一步创新，实现实用、经济高效且环保的诊断解决方案。
