Bordin Dmitry, Livzan Maria
Department of Pancreatic, Biliary and Upper GI Tract Diseases, A.S. Loginov Moscow Clinical Scientific Center, Moscow 111123, Russia.
Department of Propaedeutic of Internal Diseases and Gastroenterology, Russian University of Medicine, Moscow 127006, Russia.
World J Gastroenterol. 2024 Apr 7;30(13):1851-1858. doi: 10.3748/wjg.v30.i13.1851.
Currently, the diagnostic strategy for chronic gastritis (CG) is aimed not just at fixing the presence of gastric mucosal inflammation, but also at gastric cancer (GC) risk stratification in a particular patient. Modern classification approach with the definition of the stage of gastritis determines the need, activities and frequency of dynamic monitoring of a patient. However, this attitude to the patient suffering from CG was far from always. The present publication is a literature review describing the key milestones in the history of CG research, from the description of the first observations of inflammation of the gastric mucosa, assessment of gastritis as a predominantly functional disease, to the advent of endoscopy of the upper digestive tract and diagnostic gastric biopsy, assessment of the role of infection in progression of inflammatory changes to atrophy, intestinal metaplasia, dysplasia and GC.
目前，慢性胃炎（CG）的诊断策略不仅旨在确定胃黏膜炎症的存在，还旨在对特定患者进行胃癌（GC）风险分层。现代胃炎分期定义的分类方法决定了对患者进行动态监测的必要性、活动及频率。然而，对CG患者的这种态度并非一直如此。本出版物是一篇文献综述，描述了CG研究历史中的关键里程碑，从首次对胃黏膜炎症的观察描述、将胃炎评估为主要功能性疾病，到上消化道内镜检查和诊断性胃活检的出现，评估感染在炎症变化进展为萎缩、肠化生、发育异常和GC过程中的作用。
