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斯坦纳特型肌强直性营养不良的患病率及医疗服务利用情况:一项基于人群的横断面研究。

Prevalence of Steinert's Myotonic Dystrophy and Utilization of Healthcare Services: A Population-Based Cross-Sectional Study.

作者信息

Hernáez Leticia, Zoni Ana Clara, Domínguez-Berjón María-Felicitas, Esteban-Vasallo María D, Domínguez-González Cristina, Serrano Pilar

机构信息

Nursing Department, Faculty of Medicine, Universidad Autónoma de Madrid, 28040 Madrid, Spain.

Subdirección General de Información Sanitaria, Ministry of Health, 28071 Madrid, Spain.

出版信息

Healthcare (Basel). 2024 Apr 16;12(8):838. doi: 10.3390/healthcare12080838.

DOI:10.3390/healthcare12080838
PMID:38667600
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11050373/
Abstract

Myotonic dystrophy type I (MDI) is the most common muscular dystrophy in adults. The main objectives of this study were to determine the prevalence of MDI in the Community of Madrid (CM) (Spain) and to analyze the use of public healthcare services; a population-based cross-sectional descriptive study was carried out on patients with MDI in CM and data were obtained from a population-based registry (2010-2017). A total of 1101 patients were studied (49.1% women) with average age of 47.8 years; the prevalence of MDI was 14.4/100,000 inhabitants. In the women lineal regression model for hospital admissions, being in the fourth quartile of the deprivation index, was a risk factor (regression coef (rc): 0.80; 95%CI 0.25-1.37). In the overall multiple lineal regression model for primary health care (PHC) attendance, being a woman increased the probability of having a higher number of consultations (rc: 3.99; 95%CI: 3.95-5.04), as did being in the fourth quartile of the deprivation index (rc: 2.10; 95%CI: 0.58-3.63); having received influenza vaccines was a protective factor (rc: -0.46; 95%CI: -0.66-(-0.25)). The prevalence of MDI in the CM is high compared to other settings. Moreover, having any level of risk stratification of becoming ill (high, medium or low) has a positive association with increased PHC consultations and hospital admissions.

摘要

I型强直性肌营养不良(MDI)是成人中最常见的肌营养不良症。本研究的主要目的是确定西班牙马德里自治区(CM)MDI的患病率,并分析公共医疗服务的使用情况;对CM地区的MDI患者进行了一项基于人群的横断面描述性研究,数据来自基于人群的登记处(2010 - 2017年)。共研究了1101例患者(女性占49.1%),平均年龄47.8岁;MDI的患病率为14.4/10万居民。在女性住院的线性回归模型中,处于贫困指数的第四个四分位数是一个风险因素(回归系数(rc):0.80;95%置信区间0.25 - 1.37)。在初级卫生保健(PHC)就诊的总体多元线性回归模型中,女性增加了就诊次数较多的概率(rc:3.99;95%置信区间:3.95 - 5.04),处于贫困指数的第四个四分位数也是如此(rc:2.10;95%置信区间:0.58 - 3.63);接种流感疫苗是一个保护因素(rc: - 0.46;95%置信区间: - 0.66 - ( - 0.25))。与其他地区相比,CM地区MDI的患病率较高。此外,任何疾病风险分层水平(高、中或低)与PHC就诊次数和住院次数增加呈正相关。