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全球麻疹监测:趋势、挑战及对公共卫生干预措施的影响

Global Measles Surveillance: Trends, Challenges, and Implications for Public Health Interventions.

作者信息

Branda Francesco, Giovanetti Marta, Romano Chiara, Benvenuto Domenico, Ciccozzi Alessandra, Sanna Daria, Ciccozzi Massimo, Scarpa Fabio

机构信息

Unit of Medical Statistics and Molecular Epidemiology, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.

Department of Sciences and Technologies for Sustainable Development and One Health, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.

出版信息

Infect Dis Rep. 2024 Apr 16;16(2):367-379. doi: 10.3390/idr16020028.

Abstract

Measles, a highly contagious disease primarily affecting children, carries serious health risks, including complications and mortality. Vaccination remains the most effective preventive measure against measles transmission. The COVID-19 pandemic has exacerbated challenges in surveillance and immunization efforts, leaving millions of people exposed to preventable diseases such as measles. Globally accelerated immunization campaigns are critical for achieving regional elimination goals and mitigating the risk of outbreaks. Our team has developed an open-access database for global measles monitoring, facilitating standardized data collection and analysis. The analysis of measles cases from 2011 to 2023 reveals fluctuating trends, with notable increases in Africa in 2019 and 2023, indicating potential gaps in control strategies. Using an automated signal detection tool developed by the European Centre for Disease Prevention and Control (ECDC) team, we identified significant variations between World Health Organization (WHO) regions, underscoring the importance of continuous monitoring to detect epidemiological changes early. These results underscore the need for robust surveillance systems and accelerated vaccination efforts to safeguard public health.

摘要

麻疹是一种主要影响儿童的高度传染性疾病,会带来严重的健康风险,包括并发症和死亡。接种疫苗仍然是预防麻疹传播的最有效措施。新冠疫情加剧了监测和免疫工作面临的挑战,使数百万人面临麻疹等可预防疾病的威胁。全球加速免疫运动对于实现区域消除目标和降低疫情爆发风险至关重要。我们的团队开发了一个用于全球麻疹监测的开放获取数据库,便于进行标准化的数据收集和分析。对2011年至2023年麻疹病例的分析揭示了波动趋势,2019年和2023年非洲病例显著增加,表明控制策略可能存在差距。使用欧洲疾病预防控制中心(ECDC)团队开发的自动信号检测工具,我们发现世界卫生组织(WHO)各区域之间存在显著差异,凸显了持续监测以尽早发现流行病学变化的重要性。这些结果强调了需要强大的监测系统和加速疫苗接种工作以保障公众健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d671/11050389/25b1c27c74d6/idr-16-00028-g001.jpg

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