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Comparative Study on the Periodontal Parameters Used in Diagnosing Periodontitis in Puerperae and Periodontitis' Relationship with the Birth of Preterm Infants: A Case-Control Study.产妇中用于诊断牙周炎的牙周参数的对比研究及其与早产儿出生的关系:病例对照研究。
Int J Environ Res Public Health. 2024 Jan 30;21(2):156. doi: 10.3390/ijerph21020156.
2
Clinical, oral immunological and microbiological shifts during and after pregnancy.妊娠期及产后的临床、口腔免疫及微生物变化。
Clin Oral Investig. 2023 Dec 29;28(1):60. doi: 10.1007/s00784-023-05408-1.
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Estimation of serum C-reactive protein activity in periodontal health and disease and response to treatment: a clinico-biochemical study.牙周健康与疾病及治疗反应中血清 C-反应蛋白活性的评估:临床生物化学研究。
PeerJ. 2023 Dec 4;11:e16495. doi: 10.7717/peerj.16495. eCollection 2023.
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Periodontal pathogens of the interdental microbiota in a 3 months pregnant population with an intact periodontium.牙周组织完好的3个月孕期人群中牙间微生物群的牙周病原体
Front Microbiol. 2023 Nov 1;14:1275180. doi: 10.3389/fmicb.2023.1275180. eCollection 2023.
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The association between periodontal disease and risk of adverse maternal or neonatal outcomes: A systematic review and meta-analysis of analytical observational studies.牙周疾病与不良孕产妇或新生儿结局风险之间的关联:分析性观察性研究的系统评价和荟萃分析
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牙周疾病对早产和子痫前期的影响。

The Impact of Periodontal Disease on Preterm Birth and Preeclampsia.

作者信息

Tsikouras Panagiotis, Oikonomou Efthymios, Nikolettos Konstantinos, Andreou Sotiris, Kyriakou Dimitrios, Damaskos Christos, Garmpis Nikolaos, Monastiridou Vassiliki, Nalmpanti Theopi, Bothou Anastasia, Iatrakis George, Nikolettos Nikolaos

机构信息

Department of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece.

Department of Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.

出版信息

J Pers Med. 2024 Mar 26;14(4):345. doi: 10.3390/jpm14040345.

DOI:10.3390/jpm14040345
PMID:38672972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11051368/
Abstract

This review delves into the possible connection between periodontitis and negative pregnancy outcomes, such as preeclampsia and preterm birth. It highlights the potential influence of an unidentified microbial factor on preeclampsia and the effects of inflammatory responses on the rate of preterm births. Furthermore, it underscores the prevalent occurrence of oral ailments within the populace and their significant repercussions on quality of life. Hormonal fluctuations during pregnancy may exacerbate oral conditions such as pregnancy gingivitis and periodontitis, necessitating bespoke therapeutic approaches that take into account potential fetal ramifications. Periodontal disease, characterized by microbial attack and inflammatory response, results in tissue destruction and tooth loss. The oral cavity's susceptibility to bacterial colonization, which is primarily due to its role as a site for food intake, is highlighted. Furthermore, research indicates a correlation between inflammatory responses and factors such as prostaglandin E2 and IL-1β, and preterm birth. Therapeutic interventions are a focus of international research, with efforts being aimed at optimizing outcomes through larger studies involving pregnant women.

摘要

本综述深入探讨了牙周炎与不良妊娠结局(如先兆子痫和早产)之间可能存在的联系。它强调了一种不明微生物因素对先兆子痫的潜在影响以及炎症反应对早产率的影响。此外,它强调了口腔疾病在人群中的普遍发生及其对生活质量的重大影响。怀孕期间的激素波动可能会加剧诸如妊娠牙龈炎和牙周炎等口腔疾病,因此需要采用考虑到对胎儿潜在影响的定制治疗方法。牙周疾病以微生物侵袭和炎症反应为特征,会导致组织破坏和牙齿脱落。强调了口腔因其作为食物摄入部位的作用而对细菌定植的易感性。此外,研究表明炎症反应与前列腺素E2和白细胞介素-1β等因素以及早产之间存在关联。治疗干预是国际研究的重点,旨在通过涉及孕妇的更大规模研究来优化治疗效果。