亚胺培南在4℃保存的穆勒-欣顿琼脂中的稳定性。
Stability of imipenem in Mueller-Hinton agar stored at 4 degrees C.
作者信息
Turgeon P L, Desrochers C
出版信息
Antimicrob Agents Chemother. 1985 Nov;28(5):711-2. doi: 10.1128/AAC.28.5.711.
Abstract
The purpose of the present study was to measure the stability of imipenem in Mueller-Hinton agar stored at 4 degrees C over time. MICs for Staphylococcus aureus ATCC 25923, Streptococcus faecalis ATCC 29212, Escherichia coli ATCC 25922, and Pseudomonas aeruginosa ATCC 27853 were determined in triplicate daily for up to 15 days. The calculated mean time to observe a shift of one dilution in MIC endpoints was 4.33 +/- 1.25 days. For routine work, imipenem agar dilution plates should be prepared within 48 to 72 h of the test.
摘要
本研究的目的是测定亚胺培南在4℃储存的穆勒-欣顿琼脂中的稳定性随时间的变化情况。每天对金黄色葡萄球菌ATCC 25923、粪肠球菌ATCC 29212、大肠埃希菌ATCC 25922和铜绿假单胞菌ATCC 27853进行三次重复的最低抑菌浓度（MIC）测定，持续15天。计算得出MIC终点观察到一个稀释度变化的平均时间为4.33±1.25天。对于常规工作，亚胺培南琼脂稀释平板应在试验的48至72小时内制备。
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