Kwon Oh-Sung, Kim Young-Kyu, Kim Hyeon Ju
Department of Medical Information, Jeju National University Hospital, Jeju-si 63241, Republic of Korea.
Department of Surgery, Jeju National University Hospital, Aran 13gil 15, Jeju-si 63241, Republic of Korea.
J Clin Med. 2024 Apr 15;13(8):2290. doi: 10.3390/jcm13082290.
Well-known risk factors for gallbladder polyps include metabolic syndrome, age, and dyslipidemia. Jeju Island is approximately 80 km from the Korean peninsula and is divided into two administrative regions (Jeju City and Seogwipo City), with Mount Halla intervening in the center. Jeju City has higher employment and birth rates than Seogwipo City. Age and alcohol consumption differ between the two regions, and these factors may affect the prevalence of gallbladder polyps (GBPs). Therefore, we investigated the prevalence of GBPs and compared various factors, including alcohol consumption habits and age, associated with GBPs among residents in the two regions. This study included 21,734 residents who visited the Health Screening and Promotion Center of Jeju National University Hospital between January 2009 and December 2019. We investigated the prevalence and associated factors of GBPs among residents of Jeju City and Seogwipo City. The prevalence of GBPs in Jeju City and Seogwipo City was 9.8% and 8.9% ( = 0.043), respectively. The mean age and rate of high-risk alcohol intake were higher in Seogwipo City. The mean body mass index and levels of fasting blood glucose, total cholesterol, low-density lipoprotein cholesterol, aspartate aminotransferase, gamma-glutamyl transferase, and alkaline phosphatase were lower in Jeju City. This study demonstrated a significant difference in GBP prevalence between the two regions of Jeju Island. Age and alcohol consumption might contribute to this difference; however, further prospective cohort studies are warranted to confirm our findings.
胆囊息肉的知名风险因素包括代谢综合征、年龄和血脂异常。济州岛距离朝鲜半岛约80公里，分为两个行政区（济州市和西归浦市），汉拿山位于中心位置将其隔开。济州市的就业率和出生率高于西归浦市。两个地区的年龄和酒精消费量存在差异，这些因素可能会影响胆囊息肉（GBP）的患病率。因此，我们调查了GBP的患病率，并比较了两个地区居民中与GBP相关的各种因素，包括饮酒习惯和年龄。本研究纳入了2009年1月至2019年12月期间前往济州国立大学医院健康筛查与促进中心就诊的21734名居民。我们调查了济州市和西归浦市居民中GBP的患病率及相关因素。济州市和西归浦市GBP的患病率分别为9.8%和8.9%（P = 0.043）。西归浦市的平均年龄和高危酒精摄入量率较高。济州市的平均体重指数以及空腹血糖、总胆固醇、低密度脂蛋白胆固醇、天冬氨酸转氨酶、γ-谷氨酰转移酶和碱性磷酸酶水平较低。本研究表明济州岛两个地区的GBP患病率存在显著差异。年龄和酒精消费可能导致了这种差异；然而，需要进一步的前瞻性队列研究来证实我们的发现。
